Holliday Flashcards
The biggest absolute contraindication to surgery
DKA or diabetic coma
-blood sugars sky high, too many complications, infections, etc…
quantitative signs of poor nutrition, relative contraindications to surgery, eg delay if not emergent
alb v3
20% weight loss 3 mos
prealbumin/transferrin v200
ways to rescuscitate nutrition in order of preferability
po
enteral (g tube)
tpn (IV)
quantitative signs of severe liver failure, relatively contraindicating surgery, eg delay if not emergent
bili ^2
PT ^16
ammonia ^150
(or clinical encephalopathy)
how long must stop smoking for non emergent surgery
8 weeks
why is smoking a relative contraindication to surgery
impairs wound healing
especially in plastics… so must quit ^8wks for non-emergent surgery
what to watch out for in smoker waking up from anesthesia
don’t artificially sat O2 too high
in smokers/COPDers, chronic CO2 retainers, hypoxia is last respiratory drive, don’t suppress it by artificially satting too high
what does goldman’s index do and what are the most important factors
assesses cardiac risk of surgery
CHF (EF v35%) - check w echo
MI (MI v6mos ago) - check w EKG, stress test, cath (angio basically?), revascularize
arrrhythmias, elderly, aortic stenosis (late systolic crescendo decrescendo murmur), emergency surgery, also factors
what to expecially listen for on heart auscultation in preop patient`
late systolic crescendo decrescendo murmur - aortic stenosis
not good for goldman index, cardiac risks for surgery
medications to stop prior to surgery
aspirin (1-2wks prior)
NSAIDS, vitamin E (bleeding issues)
warfarin (want INR v1.5, can use Vit K)
Insulin - take half the morning dose because NPO after midnight
metformin (risk lactic acidosis)
when to get dialysis prior to surgery if CKD
24 hours prior
why do we check BUN and Cr prior to surgery?
uremic platelet dysfunction
BUN ^100 a risk for postop bleeding
numbers if preop patient at risk for uremic platelet dysfunction and postop bleed risk
BUN ^100
normal platelet count
prolonged bleeding time
Vent settings to know in SICU
Assist-Control - set TV and RR, if pt takes breath on their own the vent still gives the same TV… aka vent supports every breath whether pt or vent initiated… not good if pt tachypnic
Pressure Support - pt RR but boost of pressure (8-20) from vent, *important in weaning
CPAP - pt RR and TV but vent pressure all the time to keep alveoli open
PEEP - pressure given (5-20) at end of cycle to keep alveoli open *used in ARDS and CHF
vent setting important in ARDS and CHF
PEEP pressure given (5-20) at end of cycle to keep alveoli open
vent setting important in weaning
Pressure Support
pt RR but boost of pressure (8-20) from vent, *important in weaning
routine test to check while pt on vent
ABG
PaO2 PaCO2 pH
pt on vent
PaO2 too low
PaO2 too high
PaCO2 too low, pH is high
PaCO2 too high, pH is low
inc FiO2 dec FiO2 (free radical damage can worsen ARDS)
dec TV more than RR
inc TV more than RR
(TV multiplicative, also, changes ventilation of functional space only, whereas RR changes ventilation of dead space as well… but consider adjusting RR if lung perf or something a concern… i think…)
adjust minute ventilation
RR or TV
MV = RR x TV
adjust vent for PaCO2 and pH off balance
PaCO2 too low, pH is high
-dec TV (preferred to dec RR because more bang for buck, no dead space involvement)
PaCO2 too high, pH is low
-inc TV (preferred to inc RR)
Which is more efficient, adjusting TV or RR?
TV, changes functional ventilation only
while RR involves dead space as well as functional volume
Approach to acidosis
pH v7.4
check HCO3 and pCO2
-if both high, respiratory acidosis
-if both low, metabolic acidosis
check anion gap (Na - Cl - HCO3… 8-12 wnl) if metabolic
- GAP metabolic acidosis MUDPILES methanol uremia dka polyetheleneglycol/peraldehyde isoniazid lactate ethanol/etheleneglycol salicylates
- NONGAP metabolic acidosis Diarrhea, Renal Tubular Acidoses, abuse of Diuretics
MUDPLES
for anion gap (Na - Cl - HCO3 = ^12) metabolic acidosis
methanol uremia dka polyetheleneglycol/peraldehyde isoniazid lactate salicylates
non-gap metabolic acidosis etiologies
diarrhea - pooping out anions (HCO3…)
renal tubular acidoses
abuse of diuretics
approach to alkalosis
pH ^7.4
check HCO3 and pCO2
-both low, respiratory alkalosis
-both high, metabolic alkalosis
check urine chloride for metabolic alkalosis
-if low uCl v20, vomiting (ejecting via mouth, not via urine) NGT suction, antacids, diruetcis
-if high uCl ^20, Conn’s (hyperaldosteronism), Bartter’s, Gittleman’s
when to check urine chloride in acid/base disorder
for metabolic alkalosis (pH ^7.4, HCO3 and pCO2 both high)
- if low uCl v20, prob due to vomiting (ejecting via mouth, not via urine)
- if high uCl ^20,
what causes hyponatremia
next best step?
too much water
check plasma osmolality (rule out eg hyperglycemia making plasma sodium seem low)
assess fluid status clinically
- (edema, lung crackles), Hypervolemic hyponatremia think CHF, nephrotic syndrome, cirrhosis
- (dry mucous membranes, flat neck veins), HypOvolemic hyponatremia think diuretics, vomiting
- normovolemic hyponatremia think SIADH (get CXR! paraneoplastic of lung cancer), Addison’s (primary hypoaldosteronism… hypocortisolism…), hypothyroid
3 common causes of hypervolemic hyponatremia
CHF
nephrotic syndrome
cirrhosis
next step if suspect SIADH
CXR
paraneoplastic hormone of lung cancer…
how to treat hypervolemic hyponatremia?
fluid restriction, diuretics
common causes = CHF, nephrotic syndrome, cirrhosis
how to treat hypovolemic hyponatremia
IV normal saline
when to use 3% (hypertonic) saline
for severely symptomatic hyponatremia
eg seizures, AMS
or Na very low (eg v120)
how quickly to replete sodium?
why not faster?
.5-1 mEq / hr
or 12-24 mEq/day
careful not to correct too quickly (central pontine myolenolysis is life-threatening)
treat hypernatremia
what to watch out for
replete fluid with D5W or hypotonic fluid
don’t decrease more than 12-24 mEq / day because cerebral edemia
qt interval in calcium abnorms
prolongued qt - hypocalcemia
short qt - hypercalcemia
bones stones groans psychiatric overtones short QT
hypercalcemia
appropriate next best step if calcium too low or too high
ekg
to make sure pt not at risk for torsades (hyperca short qt, hypoca long qt)
paralysis ileus ST depression U waves
hypokalemia
treat hypokalemia
watch out for
replete K+ po or IV
check renal function first, if compromised you can make hyperkalemic pretty quick
signs of hyperkalemia
peaked T waves
prolonged PR and QRS
sine waves
treat hyperkalemia
Ca-gluconate to stabilize cardiac membrane
insulin and glucose to shift K+ into cells
K exlate to reduce GI absorption
dialysis last resort
Ideal maintanence IVFs
and how much to give
D5 1/2 NS \+ 20 KCl if peeing 100ml/kg/day up to 10kg 50ml/kg/day next 10kg 20ml/kg/day all above 20kg
why are enteral feeds preferred to tpn
maintains health of gut mucosa
prevents bacterial translocation
risks of TPN
acalculous cholecysitis hyperglycemia liver dysfunction zinc deficiency other electolyte issues
TF
pt w 3rd degree burn can’t feel it
Tish Fish
can’t feel 3rd degree burn - to fascia, nerves destroyed
but 2nd and 1st degree burns around it will hurt very much
so something will hurt
feared complication of circumferential burns
compartment syndrome
how to clinically check airway in burn patient, what to watch out for, how to react?
singed nose hairsm, wheezing, soot in mouth/nose
watch out for laryngeal edema
low threshold for intubation
burn patient with confusion, headache, cherry red skin
next best test?
Treat?
carboxy-Hb (CO poisoning)
give 100% O2
consider hyperbaric treatment if severe poisoning
clot in elderly think…
cancer
clotting in setting of edema, htn, foamy pee think…
nephrotic syndrome
antithrombin III one of the first proteins to be urinated out…
is nephrotic syndrome a risk for bleeding or clotting?
clotting
antithrombin III one of the first proteins to be urinated out…
young person with clot and positive family hx think…
factor V leiden…
coag factor V insensitive to activated protein C, which is an anticoagulant… so these pts hypercoagulable
what can’t we give someone with ATIII deficiency
heparin
because it won’t work
because heparin potentiates the action of antithrombin III, thereby preventing activation of factors II (thrombin), IX X XI XII
yount woman with multiple spontaneous abortions think…
lupus anticoagulant
postop pt with clots but low platelets think…
treat with…
HIT
heparin induced thrombocytopoenia
from antibody against heparin bound to platelet factor IV PF4
anticoagulate with a non-heparin anticoagulant, like argatroban or bivalirudin (direct thrombin inhibitors)
young women with bleed and isolated decrease in platelets think…
ITP
immune thrombocytopenia
idiopathic thrombocytopenic purpura
immune thrombocytopenic purpura
caused by acquired autoantibodies against platelet antigens
normal platelets but inc bleeding time and PTT think…
eg in woman with heavy periods, nose bleeds, easy bruising…
von Willebrand disease
(problem of platelet Function, not number)
inherited mut impairing von Willebrand factor function
low platelets high PT PTT BT low fibrinogen high d-dimer shistocytes on smear think...
DIC
disseminated intravascular coagulation
caused by gram negative sepsis (via LPS), OB stuff, carcinomatosis
define carcinomatosis
multiple carcinomas develop simultaneously, usually after dissemination from a primary source
implies more than spread to regional nodes and even more than just metastatic disease
rule of 9’s for burn victims
estimating body surface area
head and arms are 9%
torso front and back are 18% each
legs are 18% each
in kids,
head is 18%, so are torso front and back each
arms are still 9%
legs are 14%
abx for burn victim?
yes
but TOPICAL
NOT PO or IV because those breed resistance…
-Silver and Sulfadiazine Don’t Penetrate Eschar and cause Leuokopenia
-Mafenide Penetrates Eschar but Hurts like hell
-Silver Nitrate Doesn’t Penetrate Eschar and causes HypoKalemia and HypoNatremia
first best step for
chemical burn
electrical burn
wash/irrigate for 30 minutes
EKG, if abnormal, monitor on telemetry for 2 days (also if LOC loss of consciousness)
blood on urine dipstic but no RBCs on microscopic exam in burn pt think…
check…
rhabdomyolysis
(especially in electrical burn pt)
causing myoglobinuria
causing renal failure
check K+, if massively released from dying cells can cause arrhythmia
pressure diagnostic for compartment syndrome…
compartment pressure ^30mmhg
… but correlate clinically… 5 P’s…
trauma pt unconscious… what to do…
intubate!
trauma pt GCS v8… what to do…
intubate!
pt stung by bee, getting stridor, tripod posturing… what to do…
intubate!
guy stabbed in neck, GCS 15, talking to you, but expanding mass in lateral neck… what to do…
intubate!
guy stabbed in neck, subcutaneous emphysema w palpation… what to do…
intubate! carefully, with a fiberoptic bronchoscope, because may be an airway laryngeal tracheal bronchial injury
huge facial trauma, oral and nasal airways obscured and difficult to identify, GCS v 8… what to do…
crycothyroidotomy
don’t intubate if you can’t make out the airway at all due to trauma