gen surg 12/30/16 Flashcards
presentation of acute mesenteric ischemia
periumbilical abdominal pain (sudden onset, poorly localized (visceral), often severe, with nausea amd vomiting)
pain out of proportion to exam (severe pain but minimal diffuse tenderness, early)
hematochezia (late), also localized pain peritoneal signs and sepsis if infarct develops
lab findings in acute mesenteric ischemia
leukocytosis
amylase and lipase elevated
metabolic acidosis (lactate)
diagnose acute mesenteric ischemia
ct preferred to mr angiography
mesenteric angiography if still unclear
pres
labs
dx
mesenteric ischemia
periumbilical abdominal pain (sudden onset, poorly localized (visceral), often severe, with nausea amd vomiting)
pain out of proportion to exam (severe pain but minimal diffuse tenderness, early)
hematochezia (late), also localized pain peritoneal signs and sepsis if infarct develops
leukocytosis
amylase and lipase elevated
metabolic acidosis (lactate)
hemoglobin elevated (hemoconcentration)
ct preferred to mr angiography
mesenteric angiography if still unclear
most common causes of acute mesenteric ischemia
cardiac embolism (afib, valvular dz/vegetations, cv aneurysm
thrombosis (pad, low cardiac output state)
acalculous cholecystitis
pres
usually in critically ill hospitalized pt
jaundice, urq pain and/or mass
tf
urge to defecate is common with acute mesenteric ischemia
t
tf
acute severe abdominal pain in alc wdrwl
f restlessness diaphoresis tachycardia seizures hallucinations ams
acute severe ab pain less likely
presenation of abdominal abscess
subacute fever focal tenderness weight loss
bowel sounds in opioid wdrwl
increases
gi sx, flu-like sx, sns sx (mydriasis, agitation, anxiety)
postop pt w fev leuk parotid inflammation think…
how to prevent…
acute bacterial parotitis
(most common in dehydrated postop pts amd elderly)
prevent w hydration and oral hygiene
most common bug in acute bacterial parotitis
staph aureus
tf
incentive spirometry had been shown to reduce postop pulmonary complications by 50%
t
uworld 2016
why are beta blocker used perioperatively
to reduce the risk of ischemia
tf
perioperative abx for routine abdominal surg
t
who gets “polysaccharide vaccine” and what does it prevent?
pts ^65yo
strep pneumo
acute bacterial parotitis
pres
prev
tx
parotid pain aggravated by chewing
fev leuk tender swollen erythematous parotid common
hydration and oral hygiene
tx staph aureus usually
normal total bilirubin
.1-1 mg/dl
chronic mesenteric ischemia aka
intestinal angina
intestinal angina aka
chrinic mesenteric ischemia
etiology of sphincter of oddi dysfunction
any inflammatory process
(post surgical, pancreatitis, etc…)
opioid analgesics can cause sphimcter contraction and precipitate sx
sphincter of oddi dysfunction define pres dx tx
dyskinesia or stenosis blocking bile flow
recurrent episodic ruq or epigastric pain
ast alt all phos ele
us dilated bile duct no stones
MANOMETRY gold standard
sphincterotomy usually
bile reflux gastritis
pathogenesis
pres
incompetent pyloric sphincter (eg postop gastric surg) duod can reflux into stomach and esophagus
vom, freq heartburn, ab pain
define choledocholythiasis
gallstones in common bile duct
chronic mesenteric ischemia
pres
“intestinal angina”
dull post prandial epigastric pain due to atherosclerotic narrowing
dx ibs
ab pain bowel habit change (diarrhea vs constipation) etc
ro other dxs (infection, lactose intolerance…)
lab tests and imagimg studies to dx ibs
none
ab pain bowel habit change (diarrhea vs constipation) etc
ro other dxs (infection, lactose intolerance…)
normal hb
12-16 f
13.5-17.5 m
blunt abdominal trauma
left sided ab pain
anemia
think…
splenic injury
blunt abdominal trauma with evidence of hemorrhage must think…
splenic injury
presentation of splenic injury after blunt abdominal trauma
hypotension pleuritic chest pain left abdominal wall bruising luq tenderness guarding referred left shoulder pain from hemorrhage irritating left hemidiaphragm, worse w inspiration (kehr's sign)
workup for suspected splenic injury after blunt abdominal trauma
cbc for anemia
FAST focused assessment w sonography for trauma, for hemodynamically unstable (eg sbpv90) or stable and alert, ct if fast normal
if not alert can consider straight to ct
manage splenic injury after blunt abdominal trauma
hemodynamically unstable, fast positive, or ct positive - operate (repair preferred to removal and immunize against encapsulated bact)
hemo stable, fast neg, ct neg or minimal splenic inj - non-op serial exams and close obs
between, mgmt may vary
splenic inj after blunt ab trauma
pres
dx
tx
hypotension, pleuritic chest pain, left abdominal wall bruising, luq tenderness, guarding
referred left shoulder pain
cbc
fast focused assessment w sonography for trauma
ct if fast normal
op (repair preferred to removal and immunize against encapsulated bact) if hemo unstable or imaging positive
conservative serial exams and close obs if stable and imaging negative or minimal splenic inj on ct
gray between…
tf bp 113/71 hr 116 hb 11.8 in 25 yo m w blunt abdominal trauma is sufficient to warrant concern for hemorrhage
t
male hb nl 13.5-17.5
suspect splenic inj w blunt ab trauma
when is peritoneal lavage used in diagnosis of splenic injury
hemodynamically unstable w equivocal fast (focused assessment w sonography for trauma) or emergency us or ct unavailalable
(used to be used more before good us and ct available)
when is urgent exploratory laparotomy performed for pt after blunt abdominal trauma
hemodynamically unstable w positive fast (focused assessment w sonography for trauma)
or stable with significant injury on ct ab
presentations of colon cancer
asymptomatic screen (colonoscopy)
postmenopausal / man w iron deficiency anemia
change in stool caliber
alternating bowel habits (d/c)
weight loss
colon cancer found on colonoscopy… next steps
ct scan to stage
chemo (eg folfox or folfiri)
radiation
what is folfox
folinic acid (leucovorin) - supplies cofactor blocked by mtx or here enhances activity of 5fu by stabilizing 5-dUMP binding to thymidylate synthetase, depleting thymidine triphosphate needed for dna synth
f 5fu fluorouracil (pyrimidine antimetabolite)
ox oxaliplatin (alkylating)
what is folfiri
folinic acid (leucovorin) - supplies cofactor blocked by mtx or here enhances activity of 5fu by stabilizing 5-dUMP binding to thymidylate synthetase, depleting thymidine triphosphate needed for dna synth
f 5fu fluorouracil (pyrimidine antimetabolite)
irinotecan (binds topo I /DNA complex preventing religation of cleaved DNA strand… s-phase cell death
treat FAP
familial adenomatosis polyposis
-prophylactic cholectomy
otherwise tons of polyps, premalignant by age 18, malignant by 28, dead by 38…
good vs bad colonic polyps
good
-pedunculated, small, tubular
bad
-sessile, large, villous
how long to repeat colonoscopy
normal - 10 years
polyp - 5 years
cis carcinoma in situ - 3 years
dysplasia - 1 year
(worse it soudns, sooner back)
ulcerative colitis
deep vs superficial
continuous vs skip
tx
superficial
continuous
medical tx… but 8 years post diagnosis malignant conversion likely so consider q1y screens and prophylactic colectomy
crohn’s dz
deep vs superficial
continuous vs skip
transmural (fistula forming, fecal soiling)
skip
how will surgeon treat crohn’s dz
may symptomatically remove fistulas (transmural thickness lesions)
but mostly medically managed
(ppx colectomy for ulcerative colitis not crohn’s)
hemorrhoids
which type bleed
which type hurt
internal bleed don’t hurt
external hurt itch don’t bleed
dx hemorrhoid
gross visual - external
anoscopy - may be needed for internal
treat hemorrhoids
creams (preparation h)
sitz baths…
internal - band
external - resect (v50% anal circumference to reduce chance of scarring and stricture)
what is a sitz bath
sitz bath is a warm, shallow bath that cleanses the perineum, which is the space between the rectum and the vulva or scrotum. A sitz bath can be used for everyday personal hygiene. It can also provide relief from pain or itching in the genital area
presentation of ulcerative colitis
bloody bowel movements
weight loss
where will colon cancer cause constipation vs bleeding
right - bleeding (stool loose enough to squeeze by)
left - constipation (stool dry and gets blocked up)
anal fissure path pres dx tx
tight sphincter… constipation… tears with passage of big lump… scars smaller
pain on defecation that lasts for hours (longer than defecation pain vs relief w IBD…)
grossly visualize / clinical dx
nitroglycerin paste to try to relax botulinum topical lidocaine (numbs and loosens) sitz baths (good idea to soften stool in addition..) lateral internal sphincterotomy
LEEP procedure stands for…
loop electrosurgical excision procedure
- removes abnormal tissue by cutting away with thin wire loop carrying electrical current
- -eg for cervical cancer
2 big cancers colorectal surgeons will treat
colon cancer
anal cancer
anal cancer path pres dx tx
anoreceptive sex - hpv - scc
msm (screen for HIV), mass… brbpr
anal pap, bx
chemo and radiation (nIgro protocol)