Histology of the Urinary System Flashcards
Function of the kidneys
Filter Blood
Dispose Nitrogenous Waste
Regulate balance of H20 electrolite
Contents of the Outer layer of the Renal capsuel
Lots of Collagen Fibers
Some fibroblasts
Contents of the Inner Layer of the Renal capsule
Fewer collagen
Lots of Fibroblasts
Macroscopic Structures of the Medulla
Renal Pyramids
Renal Columns
Renal Pyramids
Base faces cortex
Apex is the renal medulla
Renal Columns
In between the Pryamids
Histology of the Renal Cortex
Renal Corpuscles
Associated tubules
Histology of the Medulla
Straight tubules leading to the papilla
Collecting ducts
Vasa recta
Contents of a Renal Lobe
Renal Pyramid
Overlying Renal Cortex
Half of each adjacent renal column
Vascular Drainage to/from Kidneys
Aorta to Renal a to Segmental a to Lobar a to Interlobar a to Arcurate a to Lobular a to Interlobular a to Afferent arteriole to Glomerular capillaries to Efferent arterioles to Peritubular capillaries and Vasa recta to Interlobular v to Lobular v to Arcurate v to Interlobar v to Renal vein to IVC
Filtration of the Kidney
Fluid is squeezed of the glomerular capillary bed
Reabsorption of the kidney
Most nutrients, water, and essential ions are returned to the blood of the peritubular capillaries
Secretion of the Kidney
Moves additional undesirable molecules into tubule from blood of the peritubular capillaries
Nephron
Structural and functional unit of the kidney
Parts of the Nephron
Renal Corpuscle
Renal Tubule
Renal Corpuscle
Filtration site in the Nephron
Renal Tubule
Site of reabsorption and secretion of the Nephron
Where does a nephron drain
Collecting tubule
Collecting duct
Multiple nephrons drain into 1 collecting duct
Renal Corpuscle
Where glomerular filtration occurs
What are the 2 parts of the renal corpuscle?
Glomerulus
Bowman’s Capsule
Glomerulus
Tuft of capillaries comprised of 10-20 capillary loops
Glomerular cappilaries are supplied by an afferent arteriole and drained by an efferent arteriole
Bowman’s Capsule
Double walled epithelium that surrounds glomerulus
What are the 2 layers of Bowman’s Capsule?
Visceral layer = external
Parietal layer = internal
Vascular pole
Part of renal capsule where afferent and efferent arterioles enter/exit
Urinary pole
Part of renal capsule where filtrate exits Bowman’s space and enters Proximal convoluted tubule
Visceral layer of Bowman’s capsule
Modified simple squamous epithelial cells - Podocuytes
Pedicels
Extensions of Podocytes
Filtration slit
Space between Pedicels
Slit diaphragm
Semipermiable membrane covering filtration slits
Parietal layer of Bowman’s capsule
Made of Simple Squamous epithelium
Renal Tubules
Where tubular reabsorption and secretion occurs
Consists of Proximal convoluted tubules, Loop of Henle, distal convoluted tubules
Proximal Convoluted tubules Histology
Simple Cuboidal Epithelium
Long Microvilli - Brush Border
fuzzy appearance of slides
Loop of Henle contents
Thick descending limb
Thin descending limb
Thin ascending limb
Thick ascending limb
Thick descending limb cell type
Simple cuboidal epihelium
Thin descending limb cell type
Simple Squamous epithelium
Thin Ascending limb cell type
Simple Squamous Epithelium
Thick Ascending limb cell type
Simple cuboidle epithelium
Distal Convoluted Tubule Histology
Simple Cuboidal epithelium - smaller than PCT
Lots of mitochondria
Fewer microvilli
Juxtaglomerular Apparatus
Structure where afferent arteriole makes contact with ascending limb of Loop of Henle
Juxtaglomerular cells + Macula densa
Macula densa
Thickened part of ascending limb of Loop of Henle
Juxtaglomerular cells
Cells that are modified muscle cells in afferent arteriole near Juxtaglomerular apparatus
Collecting ducts
Collect urine from DCT
Collecting ducts cell tupe
Simple cuboidal epithelium
Urine drainage
Collecting tubule to Collecting duct to Papillary duct to Minor Calyx to Major Calyx to Renal Pelvis to Ureter to Bladder to Urethra
Ureter
Muscular tube 10-12 inches
Peristalsis propels urine from kidney to bladder
Muscular layers of the Ureter and Urethra
Inner longitudinal
Outer Circular
Outermost longitudinal
Divisions of the male Urethra
Postatic
Membranous
Spongy
Cells of Prostatic urethra
Urothelium
Cells of the Membranous Urethra
Stratified columnar
Pseudostratified columnar
Cells of the Spongy Urethra
Stratified columnar
Pseudostratified columnar
Female urethra cell type
Initially urothelium, then stratified squamous distally