Development of the Urinary System Flashcards

1
Q

What embryonic layer derives the Urinary System?

A

Intermediate Mesoderm - between paraxial mesoderm and splanchnic mesoderm

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2
Q

Development of the Pronephros

A

Marker that sets up the rest of kidney development
Bilaterally develop on day 23
Consists of solid intermediate mesoderm rod connected to epithelium lined buds
Rudimentary - degenerates within a few days

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3
Q

Mesonephros

A

Functions as primitive kidney with primitive nephrons

Develop in weeks 4-10, funcitonal at week 6

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4
Q

What does the Mesonephros consist of

A

Mesonephric vesicles
Mesonephric Tubules
Mesonephric Ducts

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5
Q

What arises from the Mesonephric Vesicles

A

Bowman’s capsule

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6
Q

What arises from the Mesonephric Tubules

A

Tubular part of nephron

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7
Q

What arises from the Mesonephric Ducts?

A

Collecting duct

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8
Q

How does the Mesonephric duct develop?

A

Grows caudally toward cloaca
Hollows caudal to cranial upon contact with cloaca
Diverticulum develops

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9
Q

Metanephros

A

Becomes the permanent kidney

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10
Q

What are the components of the Metanephros

A

Uteric bud

Metanephrogenic blastema

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11
Q

Uteric bud arises….

A

Collecting portions of the kidney - ureter, pelvis, calyces, collecting tubules

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12
Q

Metanphrogenic blastema arises….

A

Excretory portion of kidney - Bowman’s capsule, convoluted tubules, loop of Henle

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13
Q

What portions of the mesonephric ducts persists in male genitalia?

A
Duct = ductus deferens
Tubule = efferent ductules of testes
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14
Q

What is the original blood supply before the ascension of the kidneys?

A

Common Iliac artery

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15
Q

What is the terminal blood supply of the kidneys?

A

Renal arteries off of the abdominal aorta

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16
Q

What structure can block the ascension of the kidneys?

A

Common iliac artery - can lead to ectopic kidney

17
Q

What is a Horseshoe kidney?

A

When the Inferior Mesenteric artery blocks ascent and the inferior poles fuse

18
Q

What role does the urorectal septum play in urinary system development

A

Divides the cloaca into the urogenital sinus and anorectal canal

19
Q

What are the derivates of the urogenital sinus in females?

A

Urinary bladder
Urethra
Vestibule of vagina
Vestibular glands

20
Q

What are the derivatives of the urogenital sinus in males?

A

Urinary bladder
Urethra
Prostate
Bulbourethral glands

21
Q

What happens to the allantois

A

Closes off the urachus

22
Q

What does the obliterated urachus become?

A

Median umbilical ligament - under the medial umbilical fold

23
Q

What are some abnormalities that can come from the urachus?

A

Urachal cyst
Urachal sinus
Urachal fistula

24
Q

Exstrophy of the urinary bladder

A

The anterior abdominal wall fails to close