histology notes july 7

Question 1

lynph organs

Answer 1

collagen 3 - retic fibers

trabercula

free cells - macrophages, other types fo warring cells

Question 2

encapsulated?

Answer 2

3 types

caps, no caps, partial caps

Question 3

unencap lymphoid tissue?

Answer 3

free cells

loose CT - lamina

Question 4

positive selection occurs where in thymus?

Answer 4

cortex -

negative in medulla

Question 5

dendritic cells present self antigen

Answer 5

if recognize them - KILLED - if not recog, survive - mature now only 2% survive!

Question 6

dendritic cells present self antigen

Answer 6

if recognize them - KILLED - if not recog, survive - mature now only 2% survive! and go into 2dary lymphoid tissue but are virgins

Question 7

either go forward as a cd4 or ?

Answer 7

cd8

Question 8

double positive?

Answer 8

when enter cortex

Question 9

3 types of cells in medulla?

Answer 9

4, 5, 6 type type 6 are hassal’s - keratin granuls - produce thymic hormones! - and maintain medulla

Question 10

can leave via?

Answer 10

post cap venulres or efferecent lymp vessels

Question 11

some reg T cells created when?

Answer 11

instead of cd 8 or 4, some become regulataory

Question 12

does lymph node or thumus have several lobules, sevearl cortex and medulla?

Answer 12

thymus has several - lymph on has one

Question 13

mantal zone - surrounds?

Answer 13

germinal center - both of these in secondary lymphoids

Question 14

resident vs migrating dendritic cells? difference?

Answer 14

residents - branches - from mesenchymal origin (NOT blood marrow)

at edge of germinal centers

capture antigents - done by dendrites

trap that are bound to immunoglobulins or complement proteins on their surface, for recogniation by B cells -

presenting them to b cells?

Question 15

radial or intermediate sinues?

Answer 15

connect subscapular cortical to medullary -

Question 16

inner cortex?

Answer 16

houses cd4 and High Endothelial venules

in outer cortex - B cells

Question 17

medullary cords?

Answer 17

where see b cells, macrophages, plamsa cells -

Activated B cells migrate from cortex and enter medullary sinues

plamsa cells can secrete Immunogoblins directly without leaving lymph

Question 18

does spleen have a cortex and medula?

Answer 18

no.

Question 19

What are granulocytes?

Answer 19

A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. Neutrophils, eosinophils, and basophils are granulocytes. A granulocyte is a type of white blood cell.

Question 20

cells in periarterial lymph sheath?

Answer 20

T cells

B are in the nodules

Question 21

central artery

Answer 21

surrounded by T cells -

Question 22

where in spleen does destruction of RBC occur?

Answer 22

splenic cords a Billroth

Question 23

open vs closed circulation?

Answer 23

?