Histology Lab #3

Question 1

What does ARDS stand for?

Answer 1

Acute Respiratory Distress syndrome

Question 2

ARDS has multifactorial sources of injury to what areas of the lungs and what is the flow of injury leading to death?

Answer 2

Injury to respitory capillary endothelium (generally primary) and epithelium (often secondary)

Fluid build up in alveolar spaces -> less oxygen -> change in lung -> organ failure -> death

Question 3

What are the inciting causes of ARDS?

Answer 3

Inciting causes: endotoxemia, sepsis, disseminated pulmonary infections, extensive trauma, burns, transfusions, DIC, pancreatitis or aspiration of gastric contents

Question 4

What characteristics observed in a lung slide suggests ARDS?

Answer 4

An observed pink color in alveolar spaces means the alveolar spaces are filled with a pink proteinaceous fluid

Question 5

What is the labeled feature?

What is the difference between the two lung slides?

Answer 5

Hyaline cartilage

ARDS lung: alveolar spaces are filled with pink proteinaceous material and inflammatory cells

Question 6

What are the/ going on in these labeled regions?

Answer 6

Purple Heart: Fibrin
Pink Star: Dilated blood vessels
bottom purple: Inflammatory cells, Macrophages, Neutrophils and hemorrhage

Question 7

Describe the flow of repair from a damaged vessel to scaring.

Answer 7

Damaged vessel leaks fluid and fibrin -> Formation of hyaline membrane (protein, fibrin, surfactant, and cell debris) -> scaring form

Question 8

The liver tissue from a dog with Hepatocellular Carcinoma originates from what two types of cells?

Answer 8

-originates from hepatocytes (hepatic stem cells)
-carcinoma: originates from epithelial cells

Question 9

We can list differential Dx

Answer 9

1. Hepatocelluar carcinoma
2. Biliary adenocarcinoma

Question 10

We can list differential Dx
we need what?

Answer 10

1. Hepatocelluar carcinoma
2. Biliary adenocarcinoma

Question 11

What is the the two labeled parts?

Answer 11

Pink: expansile neoplasm
Blue: Compressed preexisting Hepatic parechyma

Question 12

what are the 3 labeled parts?

Answer 12

Red: expansive neoplasm
teal: portal triad
Green: compressed preexisting hepatic paranchyma

Question 13

what are the 3 labeled parts?

Answer 13

Red: expansive neoplasm
teal: portal triad
Green: compressed preexisting hepatic paranchyma

Question 14

This neoplasm is what?

Answer 14

This neoplasm is Hepatocellular carcinoma. See prompt for the reason

Question 15

What is this region above trying to make?

Answer 15

” trying to make sinusoids by neoplasm containing red blood cells”

Question 16

What is this region above trying to make?

Answer 16

” trying to make sinusoids by neoplasm containing red blood cells”

Question 17

Histiocyctic sarcoma is originated from?

Answer 17

Histiocyte + sarcoma (tumor from mesenchymal origin or nonepithelial origin

Question 18

See the image below. No question

Question 19

What is labeled as 1 and 2?

look at other parts of the slide as well.

Answer 19

1. White pulp
2. red pulp

Question 20

What are the featured figures?

Answer 20

Question 21

Answer 21

Question 22

What are the labeled parts?

Answer 22

Anisocytosis!
anisokaryosis!

Question 23

What are the labeled parts?

Answer 23

Anisocytosis!
anisokaryosis!

Question 24

Answer 24

Question 25

Answer 25

Question 26

Answer 26

Question 27

Answer 27

Question 28

Answer 28

Question 29

Answer 29

Question 30

Answer 30

Question 31

Answer 31

Question 32

Answer 32

Question 33

Question 34

Answer 34