Histology Flashcards
Epicardium (what it is and 2 layers)
Visceral layer of serous pericardium (mesothelium)
Subepicardial layer - loose connective tissue w/ nerves/vessels/fat
Pericardial cavity - serous fluid
Myocardium
Thickest layer, w/ muscles and electrical/hormone components
Endocardium (4 layers)
Simple squamos epithelium
Fibroelastic layer
Dense connective tissue layer w/ elastic fibers
Subendocardial layer w/ Purkinje fibers and nerves
3 Layers of Vessels (inside out and general components)
Tunica Intima - endothelium/subendothelium/internal elastic lamina
Tunica Media - smooth muscle layers, external elastic lamina
Tunica Adventitia - loose connective tissue, vessels, and nerves
5 Functions of Endothelial Cells in Tunica Intima
Transcytosis (pinocytosis), diapedesis, clotting secretions, vessel tone, blood cell movements (marginalization)
Tunica Media (2)
Has variable thickness of helically-arranged muscle cells
External elastic lamina only in large arteries
Vaso vasorum
Vessels that supply large vessels, in tunica adventitia
Elastic Arteries
Largest arteries, w/ >40 layers of smooth muscle and shittons of elastic fibers
Muscular Arteries
Virtually all “named” arteries, vessels w/ 3-40 layers of smooth muscle and few elastic fibers that serve as distributing a.s. Also thick external elastic lamina
Arterioles
Greatest resistance due to 1-2 layers of smooth muscle and very small lumen - largest muscle/lumen ratio
Metarterioles
Discontinuous smooth muscle - capillary sphincter to regulate flow across capillary beds
3 Specialized ChemoR and BaroR structures
Carotid Sinus - BaroR via IX
Carotid Body (b/w int and ext carotid a.s) - ChemoR via IX and X
Aortic Bodies - ChemoR via X
Capillary General Structure
Single layer of simple squamos w/ lots of pinocytotic vesicles and TJs that sits right on basal lamina w/ no muscle layer or anything. About 7-7.5 microns wide to squeeze one RBC through at a time
Pericytes
Stem cells for capillaries that sit on basal lamina just below
3 Kinds of Capillaries (& locations)
Type I - Continuous Capillaries, in muscle/lung/nervous & connective tissue
Type II - Fenestrated, pores w/ diaphragms (2 layers of PM w/ no cytoplasm) in intestines/pancreas/kidneys/endocrine glands
Type III - Sinusoidal - large pores w/out diaphragms in liver, bone marrow, spleen, lymphoid organs, and some others