Hipersensibilidad I Flashcards

1
Q

La hipersensibilidad I esta mediada por…

A

IgE
Granulocitos

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2
Q

Atopía

A

Producción IgE contra a.g. comunes como polvo y polen

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3
Q

Por donde entran los a.g. de hipersensibilidad I

A

Entrada por mucosa

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4
Q

¿Qué reconoce IgE

A
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5
Q

¿Qué pasos necesito para que se lleve a cabo una hipersensibilidad I?

A

Sensibilización
2º exposición

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6
Q

Sensibilización

A

Primera exposición
DCs reconoce a.g.→Th2→LB2→IgE→Mastocito/Eos-IgE

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7
Q

Si esta Th2 presente…

A

Th1 se inh

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8
Q

Si Th17 esta presente…

A

Treg se inh

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9
Q

LB2

A

Paso por centro germinal

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10
Q

LB1

A

No paso por SHM y se quedo en zona marginal

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11
Q

Receptor de mastocito para IgE

A

FcεR1

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12
Q

¿Donde se pega la IgE en el mastocito?

A

FcεR1

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13
Q

¿Porqué sucede la reacción de segunda exposición?

A

A.g. se pega a granulocito ya con complejo FcεR1-IgE y se siente atacado
Desgranula

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14
Q

Enfermedades de hipersensibilidad I

A

Asma
Anafilaxis
Rinitis alergica
Conjuntivitis
Dermatitis atópica
Alimentarias

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