HFDS QUIZ 1 Flashcards
CELLS Responsible for BONE REMODELING & Their Functions
OSTEOBLASTS
OSTEOCLASTS
OSTEOCYTES
BONE LINING CELLS
Build NEW BONE by producing COLLAGEN and MINERALIZING BONE MATRIX.
OSTEOBLASTS
BREAK DOWN BONE TISSUE by RESORBING MINERALS, helping in bone remodeling.
OSTEOCLASTS
MATURE BONE CELLS that MAINTAIN bone STRUCTURE and communicate with other bone cells.
OSTEOCYTES
FLAT CELLS covering bone surfaces, regulating CALCIUM EXCHANGE.
BONE LINING CELLS
HORMONES Involved in Bone Remodeling & Their Effects
Parathyroid Hormone (PTH)
Calcitonin
Vitamin D (Calcitriol)
Estrogen & Testosterone
Growth Hormone
Cortisol
INCREASES BLOOD CALCIUM by stimulating osteoclast activity.
Parathyroid Hormone (PTH)
Lowers blood calcium by inhibiting osteoclasts, promoting bone formation.
Calcitonin
ENHANCES CALCIUM ABSORPTION, aiding bone mineralization.
Vitamin D (Calcitriol)
MAINTAIN BONE DENSITY; ______ inhibits osteoclasts.
Estrogen & Testosterone
STIMULATED BONE GROWTH, especially in youth.
Growth Hormone
HIGH LEVELS can lead to BONE LOSS by increasing bone resorption.
Cortisol
A condition where bone resorption OUTPACES BONE FORMATION, leading to weakened, porous bones. It is common in aging individuals, especially postmenopausal women due to reduced estrogen levels.
OSTEOPOROSIS