heme quick facts Flashcards

1
Q

reversed

Megaloblastic. Peripheral neuropathy. MMA

A

B12 deficiency

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2
Q

reversed

Megaloblastic. No neuro symptoms

A

Folate deficiency

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3
Q

reversed

Blood loss. Microcytic. Low ferritin

A

Iron deficiency

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4
Q

reversed

Microcytic/normocytic. Normal ferritin

A

Anemia of chronic disease

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5
Q

reversed

Increased LDH, reticulocyte, indirect bilirubin. Decreased haptoglobin.

A

Hemolysis

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6
Q

reversed

Pancytopenia. Low retic count. Bone biopsy.

A

Aplastic Anemia

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7
Q

reversed

X-linked enzyme deficiency. Infection. Fava beans. Bite cells. Heinz body.

A

G6PD

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8
Q

reversed

Vaso occlusion. Hemolytic anemia. Cold, hypoxia, alcohol, infection. Howell Jowel bodies. Penicillin. Hydroxyurea.

A

Sickle Cell

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8
Q

reversed

Vaso occlusion. Hemolytic anemia. Cold, hypoxia, alcohol, infection. Howell Jowel bodies. Penicillin. Hydroxyurea.

A

Sickle Cell

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9
Q

reversed

Most common bleeding disorder. Elevated aPTT. Von willebrand factory activity. RIPA. Desmopressin.

A

Von Willebrand

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9
Q

reversed

Most common bleeding disorder. Elevated aPTT. Von willebrand factory activity. RIPA. Desmopressin.

A

Von Willebrand

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10
Q

reversed

X-linked recessive disorder. Hemarthrosis. Normal platelets. Prolonged aPTT.

A

Hemophilia

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11
Q

reversed

Thrombophilia. DVT. PE. No screening.

A

Factor V Leiden

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11
Q

reversed

Thrombophilia. DVT. PE. No screening.

A

Factor V Leiden

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12
Q

reversed

Anticardiolipin antibody. Recurrent pregnancy loss. Prolonged aPTT. Russel Viper venom test. DVT.

A

Antiphospholipid Syndrome

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13
Q

reversed

>4days. Thrombosis. ELISA. Venous limb gangrene.

A

Heparin Induced Thrombocytopeni a

13
Q

reversed

>4days. Thrombosis. ELISA. Venous limb gangrene.

A

Heparin Induced Thrombocytopeni a

14
Q

reversed

Shiga Toxin producing ECOLI 0157:H7. Quinine. Microangiopathic hemolytic anemia and thrombocytopenia.

A

Immune thrombocytopeni a

14
Q

reversed

Shiga Toxin producing ECOLI 0157:H7. Quinine. Microangiopathic hemolytic anemia and thrombocytopenia.

A

Immune thrombocytopeni a

15
Q

reversed

  1. Myeloid. Auer rod. Phi bodies. M3. all- trans-retinoic acid. >20% blasts
A

AML

15
Q

reversed

  1. Myeloid. Auer rod. Phi bodies. M3. all- trans-retinoic acid. >20% blasts
A

AML

16
Q

reversed

Children. Lymphoid. >20% blasts. TdT.

A

ALL

17
Q

reversed

Neutrophils. Basophilia. Leukocytosis. 9:22 translocation. Philadelphia chromosome. Tyrosine Kinase Inhibitor.

A

CML

18
Q

reversed

Non functioning B cells. Lyphadenopathy. Lymphocytosis. Flow cytometry. Rituximab

A

CLL

19
Q

reversed

Painless cervical lymphadenopathy. B symptoms. Reed Steinberg cells. Mediastinal mass. Excisional node biopsy

A

Hodgkin Lymphoma

19
Q

reversed

Plasma cells. IgG, IgA. Bence Jones Protein. Rouleax Formation. >10% clonal plasma cells

A

Multiple Myeloma