Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PANCE- Things I didnt know > HEME > Flashcards

HEME Flashcards

1
Q

Iron low
TIBC/ Transferrin high
Ferritin low

A

Iron Deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Iron low
TIBC/ Transferrin low
Ferritin high

A

Chronic Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Physical exam findings of iron def

A

Kiolnychia
Angular Cheilosis
Tachycardia - heart is pumping harder with low o2
Glossitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

EKG of IRON deficiency

A

Global ST depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Treatment for Thalassemia

A

Blood transfusions but ultimately splenectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

key terms - kid with pica

A

Lead poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Alcoholic with microcytic

A

Sideroblastosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name all the microcytic anemias

A

Iron def
Thalamssemia
Lead poisoning
Sideroblastosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Name all the Normocytic Nomrochromic anemias

A

Chronic disease

  • kidney disease
  • infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name all the hemolytic anemia

A

Sickle cell

G6PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what genetic disorder is sickle cell

A

X-linked recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

which anemia
Bilirubin high
LDH high
Haptoglobin low

A

Hemolytic anemias

usually -> Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Parvovirus B19 commonly causes what anemia

A

Aplastic Anemia
pancytopenia
shuts down the bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is vasooculsive crisis

A

From massive sickle cells

  • > acute chest syndrome
  • > Pain in joints, ABD
  • > Pripsm
  • > stoke
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the most lethal complication of sickle cell crisis

A

acute chest syndrome

they are tiny infarcts happening in the chest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Treatment for sickle cell

A

Hydroxurea

DONT GIVE NSAIDS LIKE TORADOL- will shut down kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What does Hydroxurea do?

A

Increases the amount of Fetal Hemoglobin

really important for Sickle cell anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What causes G6PD

A 
Fava beans 
Dapsone
Primaquine
Sulfonamides- bactrium
Chloriquines 
Primaquine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Another name for Factor 8 deficiency

A

Hemophilia A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Another name for Factor 9 deficiency

A

Hemophilia B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What genetic disorder is Hemophilia

A

X-linked Recessive

Mendelian genetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the hallmark of Hemophilia

A

Think kid with no history of trama
with red joint
not swollen but painful

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the dose for Factor 8 deficency
mild
Moderate
severe

A

12.5
25
50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the dose for Factor 9 deficency
mild
Moderate
severe

A

25
50
100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Most common inherited bleeding disorder
Von Willebrand disease
26
Plts normal Bleeding time - prolonged PT normal PTT normal
Von Willebrand disease | von williebrand activity level- decreased * most important test
27
Treatment for Von Willebrand disease
``` Cryoparcipitate F8 itself DDAVP *Tranexamic Acid- Block fibrinolysis *Amino-Caproic Acid - Blocks fibrinolysis ```
28
Treatment for an acute bleed due to Von Willebrand disease
Estrogen
29
What are some inherited Hypercoaguable states
1. Factor V leidin | 2. protein C or S deficiency
30
Treament for Idiopathic Thrombocytopenic purpura - ITP
1. Steroids 2. IVIG * 3. Platelets 4. Splenectomy 5. new drugs- Rhogam, Rituximab
31
Key terms for this diagnosis - | Kid with recent infection or vaccines then bruising, low plt levels, enlarged spleen
Idiopathic Thrombocytopenic purpura - ITP
32
Key terms for this diagnosis - | Fever, confused/lethargic , Low RBC count, low plts, elevated BUN
``` Thrombotic Thrombocytopenic Purpura - TTP "FATRN" Fever Anemia Thrombocytopiena low plts renal failure cNs symptoms ```
33
Key terms for this diagnosis- Microangiopathic hemolytic anemia with gross hematuria CNS symtoms- headache, aphasia low plts
Thrombotic Thrombocytopenic Purpura - TTP
34
What drug is most commonly the cause of Thrombotic Thrombocytopenic Purpura - TTP
Clopidogrel others- Quinine, Ticlopidine
35
What can kill a patient with Thrombotic Thrombocytopenic Purpura - TTP
accidentally giving them plts
36
What enzyme is absent in TTP causing plt & vWF not to get broken down leading to plt clots "thrombpocytopenia"
ADAMTS-13 | it is the enzyme needed to break down the VWF /PLT strand
37
Treatment for TTP
1. Freash Frozen Plasma PLTS WILL KILL THEM 2. Splenectomy 3. IVIG
38
Key terms for this diangosis- | kid with Microcytice hemolytic anemia, low plts, and acute renal failure
Hemolytic Uremia Syndrome
39
Hemolytic Uremia Syndrome | what in the history should make you think this
KID history of BLODDY DIARRHEA ! - Ecoli ate rare meant, petting zooe, daycare, swimming
40
Most common cause of Hemolytic Uremia Syndrome
E Coli - O157-H7 | Shiga like toxin
41
Treatment for Hemolytic Uremia Syndrome
``` Support them admit for fluids RBC sometimes need hemodialysis NO ANTIBITOICS CAN MAKE WORSE ```
42
What is Heparin Induced Thrombocytopenia HIT
<150 platelets OR Drop of 50% from their baseline
43
What drug blocks the conversion of Factor X to Xa and | Prothrombn to thrombin
Heparin
44
What drug blocks the conversion of Factor X to Xa
Low molecurlar weight heparin - LMWH
45
Key terms for this diangosis- Had a hostpital stay and was given IV medication, one week later now present with DVT, PE, Gangrene, storke, MI DIC
Heparin Induced Thrombocytopenia HIT
46
Treatment for Heparin Induced Thrombocytopenia HIT
``` STOP HEPARIN do not give platelets give direct thrombin inhibitors - Argatroban -Bivalirudin -Lepirudin ```
47
Key terms for this diagnosis Adult with extreme fatigue weight loss, CBC- Myeloid stem cells with Auer Rods
Acute Myelogenous Leukemia | AML
48
Key terms for this diagnosis Child with recurrent infections, bloody nose, burising easily CBC- Blasts, Lymphid stem cell line
Acute Lymphocytic Leukemia - ALL
49
Treatment for ALL
Huge blast of Chemo then | consolidation chemo
50
Treatment for AML
Chemotherapy
51
What is a major complication when treating ALL or AML with chemotherapy ?
``` Tumor lysis syndrome when you kill the cancer cells their insides are free around the body and get suck in the kidneys and can cause renal failure Also can cause metabolic changes like high K+ High uremia High Phosphates Low Calcium ```
52
Key terms for this diagnosis Adult male 55yrs with fatigue, weight loss, anemia physical exam shows englarged spleen CBC- WBW 100,000
Chronic Myeloid Leukemia - CML | it can go acute very quickly
53
Philadephlia Chromosome 9:22
Chronic Myeloid Leukemia - CML
54
Key terms for this diagnosis Adult male 70yrs with fatigue, weight loss, recurrent infections CBC- WBW 100,000 & Smudge cells
Chronic Lymphoid Leukemia - CLL
55
BCR-ABL gene | what lukemia
Chronic Myeloid Leukemia - CML
56
Reed Sternberg cell on lymph node biopsy
Hodgkin Lymphoma
57
Key terms for this diagnosis Teenage kid that noticed a painless swollen lymph node when he drank alcohol at a party the node became painful
Hodgkin Lymphoma
58
What type of Lymphoma is most common with HIV patients
Non- Hodgkin Lymphoma
59
Which Lymphoma is the worst prognosis ?
Non- Hodgkin Lymphoma
60
What is the ANN arbor Staging for Lymphoma
1. single lymph node chain 2. 2 or more lymph nodes above the belly button 3. Lymph nodes above and below the belly button 4. Anything that has spread beyond nodes, bone,lungs, brain
61
EXAM * Treatment for Lymphoma
``` AVBD * Adriamycin Bleomycin Vinblastine Dacarbazine with chem and localized radiation ```
62
What lab value correlates with prognosis with Lymphomas
LDH high bad - cells are proliferating low good - cells are dying
63
Malignant proliferation of plasma cells
Multiple Myleoma
64
Xray- punched out skull lesions
Multiple Myleoma
65
key terms for this diagnosis- | Adult with Anemia, Bone pain, seems to get a lot of colds, lower extremity weakness
Multiple Myleoma | lower extremity weakness due to spinal cord compression
66
CBC shows Rouleaux | serum protein electrophoresis - monoclonal spike
Multiple Myleoma
67
Key terms for this diagnosis- Low blood count, High BUN count, hypercalcemia
Multiple Myleoma
68
Treatment for Multiple Myleoma
1. Thalidomide - do not give if pregnant 2. Steroids 3. Doxorubicin

PANCE- Things I didnt know (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions