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PANCE- Things I didnt know > Pharmacology - part 2 > Flashcards

Pharmacology - part 2 Flashcards

1
Q 
Drug category: 
Ranitidine 
Famotidine
Cimetidine
Nizatidine
A

H-2 receptor antagonists

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2
Q

Side effects include: gynecomastia, glalactorrhea

A

Cimetidine

H-2 receptor antagonists

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3
Q

MOA: inhibits histamine stimulation of gastric acid secretion

A

H-2 receptor antagonists

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4
Q

Drug Category:
Omeprazole
Lansoprazole
Pantoprazole

A

Proton pump inhibitors

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5
Q

MOA: inhibitis proton pump on gastic parietal cell

A

Proton pump inhibitors

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6
Q

side effects include: gastric cancer risk from achlorhydria

A

Proton pump inhibitors

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7
Q

Drug Category:
Aluminum hydroxide
magnesium hydroxide
calcium carbonate

A

“weak acids”

Anatacids

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8
Q

MOA: neutralizes HCL

A

Anatacids

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9
Q

Alumin hydroxide side effect ?

A

Anatacid that can cause constipation

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10
Q

Magnesium hydroxide side effect ?

A

Anatacid that can cause Diarrhea

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11
Q

MOA: inhibits pepsin release, increasing mucus secreation, and antimicrobial

A

Bismuth subsalicylate- pepto bismol

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12
Q

Side effects: Black stool, Reye syndrome

A

Bismuth subsalicylate- pepto bismol

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13
Q

MOA: blocks dopamine receptors in the gut

A

Phenothiazines - promethazine, prochlorperazine

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14
Q

Drug category:
Promethazine
Prochloperazine
Chlorpromazine

A

Antiemetics

Phenothiazines

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15
Q

Side effects: Parkinsonism, dystonia, tissue injury from parenteral delivery, Seizures, V. tach

A

Antiemetics
Phenothiazines
examples: promethazine, prochloperazine, chloropromazine

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16
Q

Drug category:
Ondansetron
granisetron
dolasetron

A

Antiemetics

5HT-3 serotonin

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17
Q

Drug category:
Rosuvastatin
Atorvastatin

A

HMG-CoA reductase inhibitors

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18
Q

MOA: blocks cholesterol synthesis in the liver

A

HMG-CoA reductase inhibitors

statins

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19
Q

Side effects: Myopathy, rhabdomyolysis

A

HMG-CoA reductase inhibitors

statins

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20
Q

MOA: decreases LDL, triglycerides & cholesterol

increases HDL

A

Nicotinic acid- niacin

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21
Q

Side affects: flushing, palpitations, hepatotoxicity

A

Nicotinic acid- niacin

give asprin to stop the palpitations

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22
Q

Drug category:
Gemfibrozil
Fenofibrate

A

Fibric acid derivatives - fibrates

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23
Q

MOA: inhibits peripheral lipolysis and decreases hepatic triglyceride production

A

Fibric acid derivatives - fibrates
Gemfibrozil
Fenofibrate

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24
Q

Side affects: N/V, jaundice, increase risk of myopathy or rhabdomyolysis if used with statins

A

Fibric acid derivatives - fibrates
Gemfibrozil
Fenofibrate

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25
Drug category: Eicosapetaenoic acid Docosahexaenoic acid
Omega-3-acids
26
MOA: inhibits VLDL & Triglycerides synthesis in the liver
Omega-3-acids Eicosapetaenoic acid Docosahexaenoic acid
27
Side affects: Fishy breath, GI upset, bloating, flatulence
Omega-3-acids Eicosapetaenoic acid Docosahexaenoic acid
28
Drug category: Alirocumab Evolocumab
hyperlipidemia drugs Protein convertase subtilisin/kexin type 9 - PCSK9 injection
29
MOA: inhibits LDL production
Protein convertase subtilisin/kexin type 9 - PCSK9
30
MOA: stimulates beta-2 receptors in the bronchial tree leading to smooth muscle relaxation & bronchodilation
Beta-2 agonists short acitng- albuterol long actingin- formoterol
31
Drug category: Albuterol levaalbuterol
Beta-2 agonists | short acting
32
Drug category: formoterol salmeterol olodaterol
Beta-2 agonists | long acting
33
Side effects: tachycardia, palpitations, anxiety, hypokalemia
Beta-2 agonists short acitng- albuterol long actingin- formoterol
34
Drug category: Ipratropium
Short acting anticholinergic
35
Drug category: | Tiotropium
Long acting anticholinergic
36
MOA: counteracts vagal mediated bronchoconstriction
Anticholinergics short- ipratropium long- tiotropium
37
Side effects: of this asthma drug- dry mouth and tachycardia
Anticholinergics short- ipratropium long- tiotropium
38
Drug category ? | Cromolyn
Mast cell stabilizer
39
MOA: stabilizes mast cells by preventing degranulation and release of inflammatory mediators
Mast cell stabilizer
40
Side effects: of this asthma drug- transient wheezing, drowsiness
Mast cell stabilizer
41
Drug category ? Montelukast Zafirlukast
Leukotriene receptor
42
MOA: blocks leukotriene mediated bronchoconstriction
Leukotriene receptor Montelukast Zafirlukast
43
``` Use this asthma drug if: Aspirin sensitivity asthma cigarette smoker allergic rhinitis exercise induced asthma ```
Leukotriene Montelukast Zafirlukast
44
Side effects to this asthma drug: flu symptoms, neuropsyhciatic symptoms
Leukotriene Montelukast Zafirlukast
45
Drug category? | Roflumilast
Phosphodiesterase-4-inhibitor
46
MOA: blocks inactivitaion of cAMP
Phosphodiesterase-4-inhibitor | Roflumilast
47
Phosphodiesterase-4-inhibitor Roflumilast is used for the treatment of what?
COPD
48
What COPD drug has the side effects of: suicidal thoughts weight loss
Phosphodiesterase-4-inhibitor | Roflumilast
49
MOA: prevents binding of IgE
Immunomodulators | Omalizumab
50
Drug category ? | Omalizumab
Immunomodulators for the treatment of Asthma
51
What Asthma drug has the side effects of: | anaphylaxis
Immunomodulators | Omalizumab
52
``` Drug category ? Prednisone prednisolone methylprednisolone dexamethasone ```
Steroids
53
MOA: Anti-inflammatory & immunosuppression
``` Steroids Prednisone prednisolone methylprednisolone dexamethasone ```
54
``` Side effects include: Moon face, buffalo hump, striae hyperglycemia, fluid retention PUD, catarats, psychosis adrenal suppression ```
``` Steroids Prednisone prednisolone methylprednisolone dexamethasone ```
55
MOA: prevents conversion of vitmain K to active form, which inhibits clotting factors II, VII, IX, X
Warfarin
56
``` Side effects of this drug : bleeding skin necrosis purple toe syndrome teratogenic multiple drug interactions ```
Warfarin
57
Which anticoagulation is category X
Warfarin - caterogry x
58
Drug category: Rivaroxaban Apixaban Edoxaban
Direct Xa inhibitors
59
MOA: Directly inhibits clotting factor X
Direct Xa inhibitors Rivaroxaban Apixaban Edoxaban
60
MOA: Direct thrombin inhibitor
``` Dabigatran Lepirudin Bivalirudin Argatroban desirudin ```
61
MOA: binds to antithrombin III, inhibits Xa
Heparin
62
MOA: Inhibits Xa only
Low molecular weight heparin
63
What is the reversal agent for Heparin
protamine
64
MOA: inhibits neuronal uptake of catecholamines sodium channel blockade (anesthetic affect)
Cocaine
65
Toxicity of this drug: | hypertension, hyperthermia, rhabdomyolysis, MI, seziures, V. tach
Cocaine
66
what is the treatment for Cocaine toxicity
1. Benzodiazepines 2. cooling 3. Nitrates or nitroprusside 4. Calcium channel blockers NO BETA BLOCKERS!
67
What is contraindicated in a Cocaine toxicity
BETA BLOCKERS | give them calcium channel blockers
68
MOA: causes Catecholamine release
Amphetamines- METH
69
Toxicity of this drug: Hypertension, tachycardia, hyperthermia ** Intracrainal hemorrhge rhabdomylosis
1. Benzodiazepines 2. cooling 3. Nitrates or nitroprusside 4. Calcium channel blockers NO BETA BLOCKERS!
70
MOA: binds to opioid recptors
Heroin
71
Toxicity of this drug: Hypertension, tachycardia, tachypnea Respiratory depression Miosis
Heroin
72
Treatment for Heroin overdose
Naloxone

PANCE- Things I didnt know (21 decks)

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