Hematopoietic System Flashcards

1
Q

Connective tissue that consists of a liquid matrix containing cells and cell fragments (formed elements: 45%

A

Hematopoietic System

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2
Q
  1. more than half (55%) of the total blood volume.
  2. Pale yellow fluid. Consists of 91% water and 7% proteins.
A

Plasma

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3
Q

58% of the plasma proteins.

A

Albumin

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4
Q

38% part of the immune system; transports molecules, some are clotting factors like Fibrogen

A

Globulins

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5
Q

converted to fibrin (threadlike protein that forms blood clots)

A

Fibrinogen

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6
Q

plasma without the clotting factors.

A

Serum

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7
Q

erythrocytes; most abundant. (95% of all the formed elements.)

A

Red Blood Cells

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8
Q

leukocytes

A

White blood Cells

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9
Q

thrombocytes

A

Platelets

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10
Q

process that produces formed elements.

A

Hematopoiesis

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11
Q

A hematopoiesis that occurs in several tissues such as livers, thymus, spleen, lymph nodes, and red bone marrow.

A

Fetus

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12
Q

RBC at red bone marrow; some WBCs in the lymphatic tissues.

A

After Birth

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13
Q

hemocytoblast; where all the formd elements are derived from.

A

Stem cells

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14
Q

Biconcave disk-shaped, increases the cell’s surface area.

A

RBC

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15
Q

Unable to divide.

A

RBC

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16
Q

Lifespan: 120 days in M; 110 days in F.

A

RBC

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17
Q

transport O2 (Oxygen) from the lungs to various tissues of the body; transport CO2 (Carbon Dioxide) from tissues to the lungs.

A

RBC

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18
Q

a protein chain.

A

GLOBIN

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19
Q

a red pigmented cell

A

heme

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20
Q

protein responsible for the red color. Makes up ⅓ of RBC volume

A

Hemoglobin

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21
Q

Has 4 globin (protein chain bound to heme) chains and 4 heme (red pigmented molecule; each contains 1 iron atom w/c bind to an O2 molecule.) group.

A

Hemoglobin

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22
Q

Picks up O2 in the lungs and releases O2 in other tissues.

A

Hemoglobin

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23
Q

Bright red if bound to O2, darker red if w/o bound O2.z

A

Hemoglobin

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24
Q

RBC Production Requirements

A

Iron and Vitamin B9 & B12.

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25
Q

Old, abnormal, damaged RBCs > Spleen > degraded through PHAGOCYTOSIS by macrophages > Hgb broken down and its components are recycled or excreted

A

Fate of RBC

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26
Q

Red blood count for Men

A

4.6-6.2 million per microliter, 12-18 grams.

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27
Q

Red blood count for Women

A

4.2-5.4 million per microliter, 12-16 grams.

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28
Q

overabundance of red blood cells leading to increased blood viscosity, reduced flow rates and, if severe, plugged capillaries.

A

Erythrocytosis

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29
Q

an intentional process that serves to increase the number of circulating red blood cells.

A

Blood Doping

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30
Q

abnormally low hemoglobin in each red blood cell.

A

Anemia

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31
Q

percentage of the total blood volume that is composed of red blood cells

A

Hematocrit

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32
Q

Spherical cells larger than RBCs.

A

WBC

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33
Q

NUCLEATED

A

WBC

34
Q

Leave the blood and travel by ameboid movement through tissues.

A

WBC

35
Q

protect the body against pathogens and remove dead cells and debris from the tissues by phagocytosis.

A

WBC

36
Q

most common type of white blood cells; Move into other tissues and phagocytize microorganisms and other foreign substances.

A

Neutrophils

37
Q

least common; Release histamine and other chemicals that promote inflammation.

A

Basophils

38
Q

contain cytoplasmic granules that stain bright red with eosin, an acidic stain; Involved in inflammatory responses associated with allergies and asthma.

A

Eosinophils

39
Q

smallest; Production of antibodies and other chemicals.

A

Lymphocytes

40
Q

largest; They enlarge and become macrophages.

A

Monocytes

41
Q

break down phagocytized foreign substances and present the processed substances to lymphocytes, causing activation of the lymphocytes.

A

Macrophages

42
Q

5000-9000 ___ blood cells per microliter of blood.

A

WBC

43
Q

a lower than normal WBC resulting from decreased or destruction of the red marrow.

A

Leukopenia

44
Q

an abnormally high WBC.

A

Leukocytosis

45
Q

cancer of red marrow characterized by abnormal production of one or more white blood cell type, can cause leukocytosis.

A

Leukemia

46
Q

determines the percentage of each type of white blood cells.

A

DIFFERENTIAL WHITE BLOOD COUNT-

47
Q

Smallest part of the body.

A

PLATELETS

48
Q

Fragments of cells as they derived from megakaryocytes.

A

PLATELETS

49
Q

MAJOR FUNCTION IS HOMEOSTASIS!

A

PLATELETS

50
Q

immediate but temporary constriction of a blood vessel when smooth muscle within the wall of the vessel contracts.

A

Vascular spasm:

51
Q

derived from certain prostaglandins.

A

Thromboxanes

52
Q

lining blood vessels released from endothelial (epithelial) cells.

A

Endothelin

53
Q

accumulation of platelets that can seal up a small break in a blood vessel.

A

Platelet plug formation:

54
Q

blood vessel constriction and platelet plugs alone are not sufficient to close large tears or cuts in blood vessels.

A

Blood clotting (coagulation)

55
Q

network of threadlike protein fibers called fibrin.

A

Clot

56
Q

formation of a blood clot depends on a number of proteins found within the plasma.

A

Clotting factors

57
Q

Positive feedback mechanism.

A

Blood clotting

58
Q

Clotting factors are manufactured in the liver.

A

Blood clotting

59
Q

Require vitamin K for synthesis

A

Blood Clotting

60
Q
  • require Ca2+ and the chemicals released from platelets.
A

Blood Clotting

61
Q

attached clot at the damaged or diseased areas of blood vessels.

A

Thrombus

62
Q

thrombus that breaks loose and begins to float through circulations.

A

Embolus

63
Q
  1. Clot begins to condense into a more compact structure.
  2. Platelet contraction > serum is squeezed out of the clot.
  3. Pulls the edges of the damaged blood vessel together.
A

Clot retraction

64
Q
  1. Clots are dissolved as the repair goes on.
  2. Plasminogen: inactive converted to active plasmin w/c breaks down the fibrin.
    Tissue plasminogen activator (t-PA)- can stimulate the conversion of plasminogen to plasmin.
A

Fibrinolysis

65
Q

250,000-400,000

A

Platelet count

66
Q

the platelet count is reduced , resulting in chronic bleeding through small vessels and capillaries.

A

Thrombocytopenia

67
Q

Calculates how long it takes for the blood to start clotting, which normally 9-12 seconds.

A

Prothrombin Time Measurement-

68
Q

a chemical released from injured tissues start the process of clotting.

A

Thromboplastin

69
Q

Transport gases, nutrients, and waste products.
Transport of processed molecules.
Transport of regulatory molecules.
Regulation of pH and osmosis.
Maintenance of body temperature.
Protection against foreign substances.
Clot formation.

A

Functions of the Blood

70
Q

transfer of blood.

A

Transfusion

71
Q

the introduction of a fluid other than blood,such as saline or glucose solution, into the blood.

A

Infusion

72
Q

clumping or rupture of blood cells and clotting within blood vessels.

A

Transfusion reactions

73
Q

clumping of cells.

A

Agglutination

74
Q

rupture of red blood cells.

A

Hemolysis

75
Q

Has type A antigen

A

Type A Blood

76
Q

as type B Antigen

A

Type B Blood

77
Q

has type A and type B.

A

Type AB Blood

78
Q

has neither A nor B antigens.

A

Type O

79
Q

person who gives blood.

A

Donor

80
Q

person who receives it.

A

Recipient

81
Q

Responsible for hemolytic disease of the newborn, which can occur when the fetus is Rh-positive and the mother is Rh negative.

A

Rh Blood Group

82
Q

The composition of materials dissolved or suspended in plasma can be used to assess the functioning and status of the body’s system.

A

Blood Chemistry