Hematopoietic System Flashcards

1
Q

Connective tissue that consists of a liquid matrix containing cells and cell fragments (formed elements: 45%

A

Hematopoietic System

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2
Q
  1. more than half (55%) of the total blood volume.
  2. Pale yellow fluid. Consists of 91% water and 7% proteins.
A

Plasma

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3
Q

58% of the plasma proteins.

A

Albumin

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4
Q

38% part of the immune system; transports molecules, some are clotting factors like Fibrogen

A

Globulins

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5
Q

converted to fibrin (threadlike protein that forms blood clots)

A

Fibrinogen

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6
Q

plasma without the clotting factors.

A

Serum

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7
Q

erythrocytes; most abundant. (95% of all the formed elements.)

A

Red Blood Cells

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8
Q

leukocytes

A

White blood Cells

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9
Q

thrombocytes

A

Platelets

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10
Q

process that produces formed elements.

A

Hematopoiesis

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11
Q

A hematopoiesis that occurs in several tissues such as livers, thymus, spleen, lymph nodes, and red bone marrow.

A

Fetus

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12
Q

RBC at red bone marrow; some WBCs in the lymphatic tissues.

A

After Birth

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13
Q

hemocytoblast; where all the formd elements are derived from.

A

Stem cells

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14
Q

Biconcave disk-shaped, increases the cell’s surface area.

A

RBC

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15
Q

Unable to divide.

A

RBC

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16
Q

Lifespan: 120 days in M; 110 days in F.

A

RBC

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17
Q

transport O2 (Oxygen) from the lungs to various tissues of the body; transport CO2 (Carbon Dioxide) from tissues to the lungs.

A

RBC

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18
Q

a protein chain.

A

GLOBIN

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19
Q

a red pigmented cell

A

heme

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20
Q

protein responsible for the red color. Makes up ⅓ of RBC volume

A

Hemoglobin

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21
Q

Has 4 globin (protein chain bound to heme) chains and 4 heme (red pigmented molecule; each contains 1 iron atom w/c bind to an O2 molecule.) group.

A

Hemoglobin

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22
Q

Picks up O2 in the lungs and releases O2 in other tissues.

A

Hemoglobin

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23
Q

Bright red if bound to O2, darker red if w/o bound O2.z

A

Hemoglobin

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24
Q

RBC Production Requirements

A

Iron and Vitamin B9 & B12.

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25
Old, abnormal, damaged RBCs > Spleen > degraded through PHAGOCYTOSIS by macrophages > Hgb broken down and its components are recycled or excreted
Fate of RBC
26
Red blood count for Men
4.6-6.2 million per microliter, 12-18 grams.
27
Red blood count for Women
4.2-5.4 million per microliter, 12-16 grams.
28
overabundance of red blood cells leading to increased blood viscosity, reduced flow rates and, if severe, plugged capillaries.
Erythrocytosis
29
an intentional process that serves to increase the number of circulating red blood cells.
Blood Doping
30
abnormally low hemoglobin in each red blood cell.
Anemia
31
percentage of the total blood volume that is composed of red blood cells
Hematocrit
32
Spherical cells larger than RBCs.
WBC
33
NUCLEATED
WBC
34
Leave the blood and travel by ameboid movement through tissues.
WBC
35
protect the body against pathogens and remove dead cells and debris from the tissues by phagocytosis.
WBC
36
most common type of white blood cells; Move into other tissues and phagocytize microorganisms and other foreign substances.
Neutrophils
37
least common; Release histamine and other chemicals that promote inflammation.
Basophils
38
contain cytoplasmic granules that stain bright red with eosin, an acidic stain; Involved in inflammatory responses associated with allergies and asthma.
Eosinophils
39
smallest; Production of antibodies and other chemicals.
Lymphocytes
40
largest; They enlarge and become macrophages.
Monocytes
41
break down phagocytized foreign substances and present the processed substances to lymphocytes, causing activation of the lymphocytes.
Macrophages
42
5000-9000 ___ blood cells per microliter of blood.
WBC
43
a lower than normal WBC resulting from decreased or destruction of the red marrow.
Leukopenia
44
an abnormally high WBC.
Leukocytosis
45
cancer of red marrow characterized by abnormal production of one or more white blood cell type, can cause leukocytosis.
Leukemia
46
determines the percentage of each type of white blood cells.
DIFFERENTIAL WHITE BLOOD COUNT-
47
Smallest part of the body.
PLATELETS
48
Fragments of cells as they derived from megakaryocytes.
PLATELETS
49
MAJOR FUNCTION IS HOMEOSTASIS!
PLATELETS
50
immediate but temporary constriction of a blood vessel when smooth muscle within the wall of the vessel contracts.
Vascular spasm:
51
derived from certain prostaglandins.
Thromboxanes
52
lining blood vessels released from endothelial (epithelial) cells.
Endothelin
53
accumulation of platelets that can seal up a small break in a blood vessel.
Platelet plug formation:
54
blood vessel constriction and platelet plugs alone are not sufficient to close large tears or cuts in blood vessels.
Blood clotting (coagulation)
55
network of threadlike protein fibers called fibrin.
Clot
56
formation of a blood clot depends on a number of proteins found within the plasma.
Clotting factors
57
Positive feedback mechanism.
Blood clotting
58
Clotting factors are manufactured in the liver.
Blood clotting
59
Require vitamin K for synthesis
Blood Clotting
60
- require Ca2+ and the chemicals released from platelets.
Blood Clotting
61
attached clot at the damaged or diseased areas of blood vessels.
Thrombus
62
thrombus that breaks loose and begins to float through circulations.
Embolus
63
1. Clot begins to condense into a more compact structure. 2. Platelet contraction > serum is squeezed out of the clot. 3. Pulls the edges of the damaged blood vessel together.
Clot retraction
64
1. Clots are dissolved as the repair goes on. 2. Plasminogen: inactive converted to active plasmin w/c breaks down the fibrin. Tissue plasminogen activator (t-PA)- can stimulate the conversion of plasminogen to plasmin.
Fibrinolysis
65
250,000-400,000
Platelet count
66
the platelet count is reduced , resulting in chronic bleeding through small vessels and capillaries.
Thrombocytopenia
67
Calculates how long it takes for the blood to start clotting, which normally 9-12 seconds.
Prothrombin Time Measurement-
68
a chemical released from injured tissues start the process of clotting.
Thromboplastin
69
Transport gases, nutrients, and waste products. Transport of processed molecules. Transport of regulatory molecules. Regulation of pH and osmosis. Maintenance of body temperature. Protection against foreign substances. Clot formation.
Functions of the Blood
70
transfer of blood.
Transfusion
71
the introduction of a fluid other than blood,such as saline or glucose solution, into the blood.
Infusion
72
clumping or rupture of blood cells and clotting within blood vessels.
Transfusion reactions
73
clumping of cells.
Agglutination
74
rupture of red blood cells.
Hemolysis
75
Has type A antigen
Type A Blood
76
as type B Antigen
Type B Blood
77
has type A and type B.
Type AB Blood
78
has neither A nor B antigens.
Type O
79
person who gives blood.
Donor
80
person who receives it.
Recipient
81
Responsible for hemolytic disease of the newborn, which can occur when the fetus is Rh-positive and the mother is Rh negative.
Rh Blood Group
82
The composition of materials dissolved or suspended in plasma can be used to assess the functioning and status of the body’s system.
Blood Chemistry