Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HEMATOLOGY 1 > Hematocrit and RBC indicies > Flashcards

Hematocrit and RBC indicies Flashcards

1
Q

Hematocrit reference range (Adult Males)

A

40 to 54% (0.40 to 0.54 L/L)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hematocrit reference range (Adult Females)

A

35 to 49% (0.35 to 0.49 L/L)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hematocrit reference range (Newborn)

A

53 to 65% (0.53 to 0.65 L/L)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pertain to the instrument used to determine packed cell volume (PCV)

A

Hematocrit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The volume of red blood cells that have settled is called packed cell volume

A

Hematocrit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hematocrit topmost layer

A

Fatty layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Hematocrit second layer

A

Plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Hematocrit third layer

A

Buffy coat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Hematocrit fourth layer

A

Packed RBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hematocrit bottom layer

A

Plug (4-6mm)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Length of Micro-Hematocrit Tube

A

Approx. 75 mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Inner bore of Micro-Hematocrit Tube

A

1.2 mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Volume of blood a Micro-Hematocrit Tube can hold

A

0.05 mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Length of the plug in a Micro-Hematocrit Tube

A

4 to 6 mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Capillary tubes (red banded)

A

Heparin anticoag; used for direct capillary puncture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Capillary tubes (blue band)

A

No anticoagulant/plain; used for collection with anticoagulant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Significance of air bubbles in capillary tubes

A

Air bubbles denote poor skills but do not affect the test results

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How to fill capillary tubes with a colored ring

A

Fill from the opposite end without the colored band

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Hematocrit centrifugation

A

Spin for 5 minutes at 10,000 RPM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

RPM check for hematocrit centrifuge

A

RPM must be checked periodically with a tachometer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Rodak’s Hematology centrifuge recommendation

A

Centrifuge at 10,000 g to 15,000 g for maximum packing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Test result agreement for two patient samples

A

Results should agree within 1% [+0.01 L/L]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Effect of trapped plasma on microhematocrit results

A

Causes microhematocrit to be 1% to 3% (0.01 to 0.03 L/L) higher than automated instrument results

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Automated hematocrit

A

Calculated value from RBC and MCV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Conditions with more trapped plasma

A

Sickle cell anemia, Hypochromic anemia, Spherocytosis, Macrocytosis, Thalassemia

26
Q

Effect of abnormal RBC shapes (e.g., spherocytes, sickle cells) on packing

A

inhibit complete packing

27
Q

Causes of falsely increased hematocrit

A

Dehydration, Hemoconcentration, Insufficient centrifugation, Buffy coat inclusion

28
Q

Causes of falsely decreased hematocrit

A

Hemolysis, Improper sealing, Increased AC concentration, Introduction of excess interstitial fluid

29
Q

Rule of Three

A

Used to check validity of test results for normocytic, normochromic specimens

30
Q

Rule of Three formula for RBC count

A

RBC count x 3 = Hb +/- 3

31
Q

Rule of Three formula for Hemoglobin

A

Hb x 3 = Hct +/- 3

32
Q

Mean Cell Volume (MCV) measures

A

Average volume of an individual RBC.

33
Q

MCV formula

A

(HCT/RBC CT) x 10.

34
Q

MCV reference range

A

80 to 100 femtoliters.

35
Q

MCV in microcytic anemia

A

less than 80fL.

36
Q

MCV in macrocytic anemia

A

greater than 100 fL.

37
Q

Mean Cell Hemoglobin (MCH) measures

A

Average weight of hemoglobin in an individual RBC.

38
Q

MCH formula

A

(Hb/RBC count) x 10.

39
Q

MCH reference range

A

26-32 pg.

40
Q

Mean Cell Hemoglobin Concentration (MCHC) measures

A

Mean concentration of hemoglobin in the average RBC.

41
Q

MCHC formula

A

Hb/Hct x 100.

42
Q

MCHC in hypochromic anemia

A

less than 31g/dL.

43
Q

MCHC in hyperchromic RBCs

A

greater than 37 (true increase in Hereditary spherocytosis).

44
Q

MCHC reference range

A

31-37 g/dL or %.

45
Q

RBCs cannot hold more hemoglobin than

A

37 g/dL.

46
Q

Result >37 g/dL for MCHC

A

Should be recomputed due to possible interference or inaccurate measurement.

47
Q

MCH and MCHC clinical value

A

Have diminished but are valuable quality control tools.

48
Q

Polycysthemia definition

A

Increased hematocrit level above normal.

49
Q

Polycysthemia in clinical setting

A

Elevated hemoglobin and RBC count, reflecting elevated total erythrocyte volume.

50
Q

Two types of polycythemia

A

Absolute and Relative.

51
Q

Absolute Polycythemia

A

Elevated total red cell mass.

52
Q

Relative Polycythemia

A

Normal total red cell mass, increased hematocrit due to decreased plasma volume.

53
Q

Secondary polycythemia with appropriately EPO production (Absolute)

A

Decreased oxygen loading (hypoxia, high altitude, pulmonary disease, cyanotic heart disease, carboxyhemoglobinemia, methemoglobinemia, Hb M); Decreased oxygen unloading (high oxygen affinity hemoglobinopathy, biphosphoglycerate deficiency).

54
Q

Secondary polycythemia with inappropriately EPO production (Absolute)

A

Neoplasms (Wilms’ tumor, renal carcinoma, cerebellar hemangioma, hepatoma); Localized tissue hypoxia (polycystic kidney, renal artery stenosis); Post-renal transplant, acute hepatitis.

55
Q

Relative polycythemia

A

Diminished plasma volume (Dehydration, shock; Spurious Polycythemia: Stress polycythemia, Gaisböck’s syndrome.

56
Q

Secondary polycythemia with Genetic polycythemia (Absolute)

A

Primary familial congenital polycythemia (mutated Epo receptor); Chuvash polycythemia (mutated VHL gene).

57
Q

Secondary polycythemia with Primary marrow disorders (Absolute)

A

Polycythemia vera (PV).

58
Q

Polycythemia vera (PV) characteristic

A

Panmyelosis (excessive proliferation in RBCs, megakaryocytes, granulocytes).

59
Q

Polycythemia vera (PV) hallmark

A

Plethora.

60
Q

Polycythemia vera (PV) mutation

A

JAK2 V617 mutation (90%-97% of patients).

61
Q

Polycythemia vera treatment

A

Therapeutic phlebotomy (aim to maintain hematocrit < 45%) - also used for hemochromatosis

HEMATOLOGY 1 (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions