Hedgehog signalling Flashcards
1
Q
What genes are involved in the Hh loop?
A
Hh-> wingless-> engrailed
2
Q
What 2 things are added to the hedgehog protein?
A
Cholesterol molecule added
Fatty acid chain added
3
Q
What happens when Hh bind to Ptc?
A
It inhibits the inhibitory repression from Ptc on Smo
4
Q
What is included in the Ci cytosolic degradation complex?
A
Fused
Costal 2
5
Q
What does Smo recruit when it translocates to the plasma membrane?
A
Fused
Costal 2
Ci
6
Q
What does Gli1 do?
A
Activate Hh pathway
