Drosophila body plan

Question 1

What are the 3 classes of maternal genes that specify the A-P axis?

Answer 1

Bicoid
Nanos
Torso

Question 2

Why would an embryo lack anterior regons?

Answer 2

The mother lacked the bicoid gene

Question 3

Which protein activates anterior expression of hunchback?

Answer 3

Bicoid protein

Question 4

3 examples of gap genes

Answer 4

Hunchback
Giant
Kruppel

Question 5

What do pair-rule genes do? and how are they expressed?

Answer 5

They establish the parasegments

They are expressed in 7 transverse striped (every 2nd parasegment)- positions determined by gap genes

Question 6

3 examples of pair rule genes

Answer 6

Fushi tarazu
Odd paired
Even skipped

Question 7

2 differences between gap, pair rule genes and segment polarity genes genes

Answer 7

Segment polarity genes act in a cellular environment rather than a syncytial environment
Segment polarity genes encode proteins, their receptors, signalling components and T.factors- the other 2 only encode T.factors

Question 8

What do segmental polarity genes do?

Answer 8

They fix the parasegment boundaries

Question 9

3 examples of segmentation genes

Answer 9

Engrailed
Wingless
Hedgehog

Question 10

Hh maintains the expression of…

Answer 10

Wg

Question 11

Wg expression represses what?

Answer 11

Denticle formation