heart failure Flashcards
what is a syndrome
a collection of manifestations
what type of shock is CHF an example of
cardiogenic
causes of CHF
- MI
- valvular disease
- cardiomyopathy
- uncontrolled HTN
- CAD
risk factors for CHF
- smoking
- dyslipidemia
- HTN
- ischemic heart disease
- type 2 diabetes + metabolic syndrome
normally CO can increase by how much?
5 times
manifestations of left-sided HF
- activity intolerance
- cyanosis
- hypoxia
- orthopnea
- cough (with frothy sputum)
- paroxysmal nocturnal dyspnea
manifestations of right-sided HF
- dependent edema
- ascites (GI distress)
- anorexia, weight loss
- impaired liver function
what is compensated heart failure
compensatory mechanisms are triggered which mask manifestations
list the 6 compensatory mechanisms of HF
- frank starling law
- SNS
- RAAS
- natriuretic peptides
- endothelins
- cardiac hypertrophy + remodelling
the SNS aims to increase CO by
- tachycardia
- vasoconstriction
- increased contractility
name 2 natriuretic peptides and where they are secreted from
- atrial natriuretic peptide: heart muscle
- brain natriuretic peptide: ventricles d/t excessive stretching of heart muscle cells
what do natriuretic peptides cause
potent diuresis and natriuresis
what do endothelins cause
vasoconstriction
manifestations of CHF
- symptoms of impaired pumping (hypoperfusion, hypoxia, acidosis)
- in compensatory phase will be asymptomatic but have symptoms of compensation (high HR/BP, low blood volume, increased contractility, vasoconstriction)
diagnosis of CHF
- history (risk factors)
- labs (anemia, electrolytes, liver fx, renal fx)
- ECG, echo