Haemostasis - Tutorial Flashcards
What are the 3 requirements for haemostasis?
Platelets adhere via _____ and exposed _____.
vWF and exposed collagen
What cells do platelets come from?
Megakaryocytes
What happens to a platelet morphologically when it comes into contact with collagen/vWF?
Explain the 4 steps to the platelet secretion?
Explain the steps to platelet aggregation?
What are the 3 functions that vWF have?
How can you test if platelets are working properly?
Where do the critical steps of coagulation occur?
Thrombin burst results in ….
On the phospholipid surface of activated platelets.
results in a tough fibrin meshwork, trapping cells, stabilising the platelet plug.
Intrinsic vs extrinsic pathway? What is most important and what roles do they have? What is the common pathway and its importance?
Give an overview explaining how vessel injury results in a stable haemostatic plug? (talk about platelets, coagulation cascade etc).
