Haematology Flashcards
What term describes a variation in the size of erythrocytes? Or a high RDW (red cell distribution width)
Anisocytosis
What is a common cause of neutropenia?
Sepsis
Which protein facilitates the uptake of ferrous iron from the intestinal lumen into erythrocytes?
DMT1
Which protein inhibits ferroportin?
Hepcidin
(binds to ferroportin preventing the release of iron from enterocytes & macrophages)
What effect will a PPH have on the neutrophil count?
Neutrophillia
How long do are vit B12 stores in our liver last?
3-6 years
How does an iron deficiency anaemia appear on a FBC?
Low MCV
Low red cell count
Low mean cell haemoglobin
Low serum ferritin
Low reticulocyte haemoglobin
High platelet count
High red cell distribution width
Which cells fall into granulocytes?
Neutrophils
Eosinophils
Basophils
What are good sources of vit B12?
Shellfish
Fish
Liver
What term is used to describe erythrocytes with a wide variation in shape?
Poikilocytosis
Treatment of pernicious anaemia?
IM hydroxycobalamine (B12)
When does the switch from fetal to adult haemoglobin occur?
3-6 months
What are the 2 intracellular protein-iron complexes that are used to store iron?
Ferritin (in cells but small amounts in serum)
Haemosiderin (only in cells)
Which drinks reduce the absorption of iron?
Tea & coffee
What term is used to describe a blood film from a patient who has bone marrow infiltration?
(primary myelofibrosis, cancer, septic shock)
Leucoerythroblastic film
