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Pathology > Ha - Abnormal R/WCCs > Flashcards

Ha - Abnormal R/WCCs Flashcards

1
Q

primary causes of high RCC

A

polycythaemia vera
thalassaemia

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2
Q

secondary causes of high RCC

A

high altitude
AI haemolytic anaemia

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3
Q

folate deficiecny + howell jolly bodies = ?

A

coeliac

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4
Q

fe def in post menopausal woman = ?

A

blood loss

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5
Q

features of leucoerythroblastic anaemia

A

teardrop RBCs
nucleated RBCs
immature myeloid cells

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6
Q

features of immune HA

A

most common anaemia
spherocytes
direct antiglobulin test positive (Coombs)

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7
Q

Inherited vs acquired causes of haemolytic anaemia

A

Inherited = hereditary spherocytosis, G6PD deficiency, sickle cell, thalassaemia
Acquired = immune HA, disease (SLE, lymphoma)

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8
Q

Blood film / test results of HA

A

reticulocytes
Bilirubinaemia
high MCV and LDH
low haptoglobins

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9
Q

progression of low grade DIC

A

platelet activation
fibrin deposition
RBC fragmentation
platelet consumption

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10
Q

causes of raised WCC

A

reactive neutrophillia
IM
ALL / AML
CLL
eosinophilia

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11
Q

causes of reactive neutrophilia

A

pyogenic infection
steroids / inflamm / ca

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12
Q

blood film features of reactive neutrophilia

A

no immature cells
toxic granulation
vacuoles

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13
Q

blood film features of ALL/AML

A

immature cells / myeloblasts

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14
Q

blood film features of CLL

A

mature cells, myelocytes, basophils

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15
Q

causes of eosinophilia

A

parasitic infection, asthma, neoplasm, drugs, leukaemia

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16
Q

Viral (6) / illness related causes of lymphocytosis

A

EBV, CMV, toxoplasma
Hepatitis, rubella, HSV
AI, sarcoid

17
Q

lymphocytosis + mature cells = ?

A

CLL or IM

18
Q

lymphocytosis + immature cells = ?

A

ALL

19
Q

causes of lymphopenia

A

HIV or other AIDs / chemo

20
Q

what type of b cells are seen in leukaemia?

A

light chain monoclonality - either k or lamda not both

Pathology (87 decks)

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