C - Lipid Metabolism (E) Flashcards
4 types of primary hypercholesterolaemia
Familial hypercholesteraemia (type II)
Polygenic hypercholesteraemia
Familial hyperαlipoproteinaemia
Phytosterolaemia
2 types of familial hypercholesterolaemia
AD: LDLR, apoB, PCSK9
AR: LDLRAP1
What is Familial hyperαlipoproteinaemia
CETP deficiency
What is Phytosterolaemia
ABC G5 & G8
3 types of Primary Hypertriglyceridaemia
Familial type 1, IV and V
What is familial primary hypertryglyceridaemia type 1
Lipoprotein lipase or apoC IIdef
What is familial primary hypertryglyceridaemia type IV
apoA V def (sometimes)
What is familial primary hypertryglyceridaemia type V
↑synthesis of TG
3 types of Primary Mixed Hyperlipidaemia
Familial Combined hyperlipidaemia
Familial dysβlipoproteinaemia
Familial hepatic lipase deficiency
4 types of Hypolipidaemia
Aβ-lipoproteinaemia
Hypoβ-lipoproteinaemia
Tangier Disease
Hypoα-lipoproteinaemia
what is Aβ-lipoproteinaemia
MTP def
What is Hypoβ-lipoproteinaemia
Truncated apoB protein
What is Tangier Disease
HDL def
What is Hypoα-lipoproteinaemia
apoA-I mutations (sometimes)
order of density of cholesterol proteins
Chylomicron < FFA < VLDL < IDL < LDL < HDL
