Gross Brain Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Cerebellum

A

little brain separate part that attaches to the brain

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2
Q

Lobes of the Cerebrum

A

Frontal - Higher order thinking area and make decisions, think abstractly, have personality, preform movements
Temporal- memory, auditory functions
Parietal - somatic sensation and integration sensation
Occipital - vision

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3
Q

Cerebral Cortex

A
the outer layer of cerebrum
Cortex refers to tree brake 
Some parts of the cortex appear gray in color, and others appear white 
Consists more of grey matter 
Gray matter/white matter
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4
Q

What do you think underlies these differences in color?

A

Mylenations fatty covering/wrapping

White color - all the axons are due to the myline wrapping around the axons. All the whites are leaving the cell soma and coming down to the grey matter regions

Grey matter - neuron cell bodies and dendrites & somas

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5
Q

Features of the Cerebral Cortex

A

Fissures - deep grooves that divide large regions of the brain
Longitude fissure Running in sagittal plane separates left and right hemisphere

Separate frontal and temporal lobe
-Sylvian fissure or Lateral fissure

Gyri - look like the ridges around the brain
Sulcus/Sucli - valleys where the folds curl down in the grooves
Why do we have these folds?
-increasing surface area without changing the amount of space the cell takes up

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6
Q

How do we know the functions of different brain areas?

A

Classically, based of different type of injures

FMRI - Able to look at blood flow patterns in the brain and create a heatmap. If area has increase blood flow that means it’s more active
Most region have different functions and not easy and difficult to make large studies and basing results off a small amounts of ppl

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7
Q

Gyri

A

Central Sulcus divide frontal lobe and parietal lobe
Arise from the longitude fissue and straight down the lateral fissure
-Precentral gyrus - it’s functions primary motor cortex and initial our movements
-Post central gyrus - nuerons sensation and interpreting here

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8
Q

The homunculus

A

-Post central gyrus/Sensory Homunculus (Superior lateral)
-Amount of area number of neurons within our motor cortex and within somastic senory cortex dedicated to parts of the body
Why?
-This is how we interact with the environment and have better sensory or perception of those areas

Motor cortex is organized simillary is based on motions and joint movements

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9
Q

Why is knowing the organization of the homunculus important clinically?

A

Underlies the deficit we see in the patients and what parts of the cortex are damaged

Feet and genitals are located within the Longitude fissure
Hands - Superior Lateral portion where the sensory motor region will be
Inferior Lateral - face/mouth is represented

Patient suffered superior lateral of the brain what functions may they not be able to do -typing on a keyboard

Patients had a stroke and killed all neurons on the motor cortex along the longitudinal fissue what might not they be able to do? - Walk, dance

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10
Q

to know

A

Motor cortex is in the precentral gyrus

At the brain stem these axons will cross over to the other side of the body and descend down to the spinal cord .

Here we have neurons in the left precentral gyrus (left motor cortex) they’re sending their axons down through the brain stem and before right before the spinal cord and go to the right side of the spinal cord and control muscles on the left side of the body.

Motor neurons in the motor cortex control muscles on the contralateral side of the body
Deccusation = when axons cross from one side of the body to other

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11
Q

Gyri of the Frontal Lobe

A

Run horizontally across the lobe

Superior frontal gyrus - it’s job is short term working memory, five mins or so
Middle frontal gyrus - Memory recall librarian specific saved memory
Inferior frontal gyrus - generating speech, picking words to say and how that word sounds (located in the left hemisphere)

Speech and language are located on the left hemisphere for most ppl.

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12
Q

Clinical Correlate: Expressive/Broca’s Aphasia

A

Damaged to the Inferior Frontal Gyrus

  • Halting, effortful speech, often less than 4 words
  • Can understand spoken language and can read but often have difficult with writing, or sign language
  • Due to damaged of the inferior front gyrus
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13
Q

Temporal lobe

A

Runs horizontal

Superior temporal gyrus - auditory processing, many neurons processing sound coming in
Middle temporal gyrus - does a little of both auditory and visual spatial processes
Inferior temporal gyrus - visual processing and spatial processing

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14
Q

Clinical Correalate: Receptive/Wernickle Aphasia

A
  • Damaged to Superior Temporal Gyrus due to stroke or traumatic brain injury
  • Difficulty processing and interpreting language incoming language (auditory or written)
  • Fluent speech but is mostly meaningless
  • Reading and writing severely impaired
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15
Q

Medial Occipital Lobe - cut in half right hemisphere of brain

A

Parieto-occipital sulcus - bc it separates parietal lobe from occipital lobe

Right above Calcarine sulcus from the LOWER half of visual field

Calcarine sulcus - Separates occiptal lobe to top and bottom interprets from visual information
Cuneus - Cuneiform bc it’s triangle form

Lingual gyrus - doesn’t have to do with speaking right below the calcarine sulcus neurons will interprets information from UPPER half our visual field

Cuneus and lingual gryus - primary visual cortex and involved with processing visual information

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16
Q

Medial Motor Cortex and Somatosenroy

A

Responsible for lower extremities and genitals
Medial portion of central sulcus
Medial portion of primary motor cortex
Medial portion of primary samotsenory cortex

17
Q

Medial Frontal Gyrus

A

-Involved with higher order thoughts and executive decision making, reflection and thinking of ourselves along the longitude fissure

Don’t confuse this area with middle frontal gyrus

18
Q

Corpus Callosum

A

Large C in cerebrum
Why do we have a big band of white matter in the middle or our brains?
-Ensures both sides of brain can communicate and send signals to each other
Axons headed to one of the hemisphere to the other side for example motor movements juggling or using both hands

19
Q

Thalamus

A

Relay center of the brain
Mid line of the brain center of brain just between the corpus callosum just Main
Train station where filtering and making sure information goes to the right place

20
Q

Hypothalamus

A

Hypothalamus - autonomic nervous system - works automatic without us thinking, sweating, changing, blood pressure, hormonal system, master controller
inferior to the thalamus

mamillary bodies of hypothalamus - they come off the hypothalamus involved with memory. connected to with the pituitary stalk Pituitary Gland

21
Q

Pituitary Gland

A

Dictates our hormones and release of testosterone and estrogen
also affects the stress response, affect our metabolism
-Sits in the Sella Turcica in the skull
-Only one Pituitary Gland

22
Q

Inferior Aspect of the Brain

A

Optic nerves - second cranial nerve coming from the eyes and bringing information back to the occipital lobe
Pituitary stalk -
mammillary bodies - memory

23
Q

Inferior Aspect of the Brain

A

Parahippocampal Gyrus - roles in memory (most medial)
Uncus -ole factory sensation and smell (Medial part)
Occipitotemporal/Fusiform Gyrus - involved with facial recognition
Inferior Temporal Gyrus - inferior temporal gyrus from the temporal side - Visual spacial processing

24
Q

Inferior Aspect of the Brain 2

A

The red arrows are pointing to the uncus, the primary olfactory center in the brain

Why might the primary olfactory center be located here?
-how tied together our memories are with smell
“ Uncus smells the funkus”

25
Q

The Brain Stem

A

Connecting to the brain and spinal cord

Midbrain - most superior part of brain stem
Pons - right in the middle and connection to cerebellum
Medulla - lowest level right before the spinal cord

26
Q

Clinical Correlate: Parkinson Disease

A

PD is caused primarily by death of dopamine-producing cells in the Substantia Nigra, which is located in the midbrain

  • Dopamine is also involved in our motor functions
  • Think of dopamine as a reward pathway, money, sex, addiction,
  • Affects motor functions - getting up from a chair, have a stoop posture, issues with amplitude of movement (see gate patterns, making small movements and slow bc how dopamine is involved with making sure movements are the right amplitude
27
Q

Brainstem Structure - Inferior Views

A

Cerebral peduncles - stalks of axons that brings information down from the motor cortex to the spinal cord
medullary pyramids - bumps contain all the axons that continue to head to the spinal cord
medullary olives - part of auto/error processing

28
Q

The Cerebellum

A

Important for balance, error correction, modifed movements. plays a role in other cognitive fucntions

Anterior lobe -
Separated by the primary fissure
Posterior lobe -
Arbor vitae - tree of life with branches (white matter) Folia - little branches

more neurons here in cerebellum than the rest of the cerebrum

balance, utilizing sensory feedback,
error correction,

29
Q

The Cerebellum

A

Purkinje neuron we find in the cerebellum
Why do you think neurons within the cerebellum have this sort of shape?
Dendrites to receive information - alot of information coming into these neurons

30
Q

The Hippocampus

A
  • Structure located deep within the medial temporal lobe

- Major function in learning and memory

31
Q

Learning and Memory: Patient H.M.

A

Famous case: Patient H.M.

  • Removal of medial temporal lobes (where hippocampus is located)
  • Unable to form new declarative (explicit) memories worked with the same researchers but couldn’t remember them
  • Intact working memory (moment to moment memory)
  • Able to remember things prior to 1 year before his surgery
  • Able to learn new skills (implicit) (for example, learn how to skateboard) could demonstrate but couldn’t remember he knew those skills

Based on the above, what does this tell us about the different types of memory? Medial temporal where the hippocampus is and turning it into a new memory (event/fact based memory)
Some new skills bypass the hippocampus

32
Q

What are the Brain Areas Involved with

A

Working Memory: Superior Frontal Gyrus
Recall of Old Memories: Middle frontal gyrus (librarian)
Formation of New Memories: Hippocampus (memories not stored here)
Procedural (Skill-Based) Memory: doesn’t involve the hippocampus and uses motor areas of the brain, cerebellum involved

33
Q

What is Cerebrospinal Fluid (CSF)?

A

Fluid formed by the choroid plexus and the walls of the ventricles that circulates through the ventricular system and around the outside of the brain
• Consists of H2O, low amounts of amino acids/proteins, ions, and no cells here, epithelial tissue
• What roles do you think CSF plays in the brain?
-take away metabolic waste,
-protection role brain will float within the CSF
-Help to slow down the movement of brain

34
Q

Ventricular System of the Brain

A

Cavities in the brain
Lateral ventricles one of eachside expand through frontal lobe out to temporal lobe and back to occipital lobe
Interventricular foramen come from each lateral ventricle
and come/connect to the Third ventricle (central) between thalami and either side the hyothalamide on either side drains into a narrow region
Cerebral aqueduct which travels to the midbrain
Fourth ventricle - very wide sits between posterior aspect of the brain stem and anterior aspect of the cerebellum
Central canal - narrow canal that runs through the spinal cord or exit go into subatrcnoid space that surrounds the brain

What type of glial cells would you expect to find here?
Ependymal cells

35
Q

Clinical Correlate: Hydrocephalus

A
  • Blockade of CSF movement results in pressure buildup in the ventricles
  • Blockage often in the foramina or cerebral aqueduct
  • Different consequences for infants and adults

Head expands due to pressure from CSF buildup. Why?
Bc carnial bones are not fused yet
• Symptoms: large head:body ratio, poor feeding, inactivity

36
Q

Hydrocephalus in Adults

A

• Bigger problem because the cranium is closed
• May be due to injury, surgery, tumors, or infection
• Symptoms may mimic dementia
• How do you think this can be differentially diagnosed from Alzheimer’s or other types of dementia?
Speed at which this happens
Wet, wobbly, wacky