Gram - negative cocci, catalase positive Flashcards
The family Neisseriaceae includes the genera
Neisseria, Kingella, Eikenella, Simonsiella, and
Alysiella
They are aerobic, nonmotile, non–spore-forming, gram-negative diplococcic
Neisseriaceae
are known
exceptions and are rod-shaped.
Neisseria elongata, Neisseria weaveri, and Neisseria bacilliformis
All species are cytochrome oxidase- and catalase-positive except for
N. elongata and N.
bacilliformis, which are catalase negative
; lipid A moiety and core LOS that differentiates
it from the lipopolysaccharide found in most gram-negative bacilli and is loosely
attached to the underlying peptidoglycan
Lipooligosaccharide (LOS) or endotoxin
protease that cleaves IgA on mucosal surfaces
Immunoglobulin A (IgA)
Humans are the only natural host for
Neisseria gonorrhoea
is an acute pyogenic infection of nonciliated columnar and transitional
epithelium; infection can be established at any site where these cells are found.
Gonococcal infections are primarily acquired by sexual contact and occur primarily in the
urethra, endocervix, anal canal, pharynx, and conjunctiva
Gonorrhea
Gnorrhea has a short incubation period of approximately
2 to 7 days
is the most common site of infection in women.
Endocervix
a gonoccal eye infection
during vaginal delivery through an infected birth canal. This can result in
blindness if not treated immediately.
ophthalmia neonatorum
The specimen of choice for genital infecctions in men
urethra
swab are inhibitory to N. gonorrhoeae
Calcium alginate and cotton
Swab to be used for N. gonorrhoeae
Dacron and Rayon Swab
typically does not grow on SBA
N. gonorrhoeae
The medium of choice for cultivation is Chocolate agar
N. gonorrhoeae
can be found as a commensal as well as an invasive pathogen
Neisseria meningitidis
It is an important etiologic agent of endemic and epidemic meningitis and
meningococcemia and rarely pneumonia, purulent arthritis, or endophthalmitis.
Neisseria meningitidis
Fulminant meningococcemia or meningitis
Neisseria meningitidis
When sepsis becomes
fulminant and spreads rapidly causing disseminated
intravascular coagulation, septic shock or haemorrhage in the
adrenal glands occurs.
Waterhouse-Friderichsen syndrome
Waterhouse-Friderichsen syndrome
Neisseria meningitidis
On Gram-stained smears from specimens such as CSF
meningococci appear as intracellular and extracellular gramnegative diplococci
Neisseria meningitidis
should be cultured on
SBA and Chocolate agar.
N. meningitidis
N. gonorrhoeae typically does not grow on
SBA
The medium of choice for cultivation is
chocolate agaer
When the bacteria adhere to the nasopharyngeal mucosa it leads in a
subclinical infection or mild symtoms.
Neisseria meningitidis
It is an important etiologic agent of endemic and epidemic meningitis and
meningococcemia and rarely pneumonia, purulent arthritis, or endophthalmitis.
Neisseria meningitidis
when sepsis becomes
fulminant and spreads rapidly causing disseminated
intravascular coagulation, septic shock or haemorrhage in the
adrenal glands occurs.
Waterhouse-Friderichsen syndrome; N.meningitidis
