Glycolysis

Question 1

Which steps are regulated in glycolysis

Answer 1

Conversion of Fructose-6-phosphate –> Fructose-1,6-bisphosphate by PFK 1

Question 2

Describe negative cooperativity

Answer 2

Enzymes that aren’t sensitive to [substrate] and bind more tightly to molecules as # of molecules bound decreases

Question 3

How is NAD+ regenerated anaerobically

Answer 3

Lactate dehydrogenase

Question 4

How is PFK-1 regulated

Answer 4

AMP positively regulates it while ATP negatively regulates it. Phosphorylation shuts it off

Question 5

How are insulin and PFK-1 related

Answer 5

insulin dephosphorylates PFK-1 thereby activating it

Question 6

What enzymes yield catalyze reactions that yield ATP in glycolysis

Answer 6

Phosphoglycerate kinase and pyruvate kinase

Question 7

What intermediate in glycolysis can be converted to serine

Answer 7

2 phosphoglycerate

Question 8

What intermediate in glycolysis can be converted to glycogen, ribose, and NADPH

Answer 8

Glucose-6-phosphate

Question 9

What can pyruvate be converted to

Answer 9

Alanine, acetyl CoA, lactate, and oxaloacetate