gluconeogenesis Flashcards
What are the four important enzymes in gluconeogenesis
Pyruvate caroxykinase, PEPCK, F6BPase, and Glucose-6-phosphatase
Where does gluconeogenesis occur
kidney, liver and intestines (?)
What is OAA converted to in the mitochondria and why
aspartate and malate because the mitochondria doesn’t have OAA transporters
where is the conversion of G6P–>glucose done
the ER
excess acetyl coA has what effect on gluconeogenesis
promotes it
excess citrate has what effect on gluconeogenesis
promotes it
Cori cycle shows
how the liver takes up alanine and lactate from other organs, turns it into glucose, and returns it to the initial organ
Cahill cycle shows
how the liver takes up alanine in muscle converts it to glucose and returns it to muscle