Glyceryl Trinitrate Flashcards
What is Glyceryl Trinitrate classified as?
Vasodilator
What is Glyceryl Trinitrate commonly shortened to?
GTN
What is the action of Glyceryl Trinitrate?
Potent vasodilator that:
- Decreases preload by increasing venous capacity
- Reducing ventricular filling pressure
- Decreasing arterial blood pressure (after load)
What are the side effects of Glyceryl Trinitrate?
- Headache
- Flushing
- Hypotension
- Syncope
- Reflex tachycardia
- Dizziness
What are the indications for administering Glyceryl Trinitrate?
- Suspected myocardial-type chest pain
- Acute Coronary Syndrome (ACS)
- Acute Cardiogenic Pulmonary Oedema
What are the contraindications for administering Glyceryl Trinitrate?
- Known severe allergic reaction
- Heart rate < 50 or > 150 beats per minute
- Systolic BP < 100 mmHg
- Acute CVA
- Head trauma
- Use of Viagra, Cialis or Levitra in previous 24 hours
What are the precautions when considering the administration of Glyceryl Trinitrate?
- Suspected inferior myocardial infarction
- Use of Viagra in previous 4 days
- Intoxication
- Cerebral Vascular Disease
What is the onset time for Glyceryl Trinitrate?
< 2 minutes
What is the duration of Glyceryl Trinitrate in the body?
20 - 30 minutes
How is this drug predominantly administered?
Sublingually
What is the dosage for Glyceryl Trinitrate?
400mcg
How many times can Glyceryl Trinitrate be repeated?
Every 5 minutes as required - no max dose
