Glucose metabolism Flashcards

0
Q

Bridge

A

-2 separate Pyruvic acids are oxidized and become acetyl coenzyme A & acetyl coenzyme A2.

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1
Q

Glycolysis

A

-1 glucose molecule breaks down into 2 Pyruvic Acids (6C–>3C)

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2
Q

Krebs

A

-Both Acetyl Coenzymes are stripped of their hydrogen protons & electrons. -all that is left of the sugar is CO2 and H2O (exhale).

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3
Q

How many total ATP are gained from Glycolysis? How?

A

8 total

  • (2ATP–>2ADP) + (4ADP–>4ATP)= 2
  • (2NAD+ –>2NADH+H)= 6
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4
Q

How many ATP are gained from Bridge?

A

6 total

-2NAD+ –> 2NADH+H = 6

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5
Q

How many ATP are gained from the Krebs step?

A

24 total

  • 6NAD+ –> 6NADH+H = 18
  • 2ADP –> 2ATP = 2
  • 2FAD–> 2FADH+ = 4
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6
Q

How many ATP are in each NADH+H?

A

3 ATP

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7
Q

How many ATP are in each FADH+?

A

2ATP

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8
Q

Where is Glycolysis located?

A

Outside the mitochondria, within the cytoplasm.

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9
Q

Where does the Bridge step take place?

A

Inside the mitochondria

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10
Q

Where does the Krebs step take place?

A

Inside the mitochondria

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11
Q

Aerobic

A

O2 required

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12
Q

Anaerobic

A

O2 not required

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13
Q

Where specifically is oxygen used and why?

A

Oxygen is used specifically in the bridge and krebs stages to oxidate the carbon atoms. That is how CO2 is released.

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14
Q

Oxidation

A

The combination of a substance with oxygen

Reaction in which the atom in an element loses an electron and the valence shell increases

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15
Q

Reduction

A

A decrease in positive valence or an increase in neg valance.

Hydrogen combines with a compound

Oxygen is removed from a compound

16
Q

Substrate Level Phosphorylation

A

Only occurs in glycolysis & Krebs.

ADP –> ATP

17
Q

Oxidative Phosphorylation

A

Occur in all 3 steps

Anytime NADH+H or FADH+ are used to create ATP

18
Q

Hydrolysis/Dehydration Synthesis

A

Chemical breakdown on a compound due to reaction with water.

Occurs anytime there is a chemical breakdown, but you can’t see it in te diagram.

19
Q

ATP Synthase

A

Synthesizes ATP

Only allows hydrogen protons through

Comes from ADP & phosphate

20
Q

Chemiosmosis

A

Proton moves across a mitochondrial membrane and ATP synthesis pumps metabolites across a membrane.

(Generation of ATP through hydrogen ions across a membrane. )

21
Q

Beta Oxidation

A

Catabolism of fatty acids in which the fatty acid chain is shortened by successive removal of two carbon fragments from the carboxyl end of the chain.

22
Q

Gluconeogenesis

A

Synthesizes glucose in the liver

23
Q

Glycogenolysis

A

The hydrolysis of glycogen to glucose

24
Q

Glycogenesis

A

Formation of glycogen from sugar

25
Q

Glycogen

A

Polysaccharide that stores glucose

26
Q

Glucose

A

Simple sugar

27
Q

What condition would cause lactic acid to build up?

A

Cells don’t receive enough oxygen&raquo_space; pH levels drop&raquo_space; cells metabolize creating lactae

28
Q

Sodium Potassium Pump

A

2k- in 3Na+ out

29
Q

What does the Electron Transport Chain do? Where is it located?

A

Located in the inner membrane of the mitochondria.

Sorts electrons and protons carried in by NADH+H and FADH+

30
Q

Malate Shuttle

A

Cells of the liver, kidneys, and heart use this resulting in 3 ATP from each NADH

31
Q

Which cells yield 36 ATP?

A

Skeletal & Nervous

32
Q

Which cells yield 38 ATP?

A

Kidney, liver, & heart