Glomerular Pathology Flashcards
What is the likely site of injury in nephrotic syndrome?
Podocyte
Subepithelial
What are the common primary causes of nephrotic syndrome?
Minimal change glomerulonephritis
Focal segment glomerulosclerosis
Membranous glomerulonephritis
What are the common secondary causes of nephrotic syndrome?
Diabetes
Amyloidosis
What is minimal change glomerulonephritis?
A childhood condition that damages the podocytes but with minimal change seen on biopsy
What is the triad of symptoms in nephrotic syndrome?
Proteinuria
Oedema
Hypoalbuminaemia
What is IgA nephropathy?
Commonest cause of glomerulonephritis
Presents with haematuria + mucosal infection
What is Goodpasture syndrome?
Anti-GBM disease
Rapidly progressively GN - antibodies to collagen IV in BM
What is the likely site of injury in nephritic syndrome?
Basement membrane
What can cause nephritic syndrome?
Goodpasture’s syndrome
ANCA vasculitis
What is the triad of symptoms for nephritic syndrome?
Haematuria
Reduced GFR
Hypertension
