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FA - GastroIntestinal > GI10 > Flashcards

GI10 Flashcards

1
Q

What products are secreted by Parietal cells?

A

Intrinsic Factor

Gastric Acid

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2
Q

What is the function of Intrinsic Factor?

A

Vitamin B12 binding protein

*Required for B12 uptake in Terminal Ileum

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3
Q

What stimulates parietal cells to secrete Gastric Acid?

A

Histamine
ACh
Gastrin

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4
Q

What inhibits parietal cell secretion of Gastric Acid?

A

Somatostatin
GIP
Prostaglandin
Secretin

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5
Q

What is the function of Gastric Acid?

A

Decrease stomach pH

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6
Q

What is secreted from Chief cells?

A

Pepsin (Pepsinogen-Inactive form)

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7
Q

What is the function of Pepsin?

A

Protein digestion

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8
Q

What stimulates Pepsin release from Chief cells?

A

Vagal stimulation

Local Acid

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9
Q

How is Pepsinogen (inactive) converted to Pepsin (active)?

A

H+

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10
Q

What is the source of HCO3- in the GI tract?

A

Mucosal cells

Brunner’s glands

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11
Q

Where are mucousal cells located?

A

Stomach
Duodenum
Salivary glands
Pancreas

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12
Q

Where are Brunner’s glands located?

A

Duodenum

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13
Q

What stimulates HCO3- secretion?

A

Pancreatic & Biliary secretion with Secretin

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14
Q

What are the products found in saliva?

A

Amylase
HCO3-
Mucins

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15
Q

What is the function of Amylase?

A

Digest Starch

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16
Q

What is the function of HCO3- in saliva?

A

Neutralizes Bacterial Acids

17
Q

What is the function of Mucins in saliva?

A

Lubricate food

18
Q

What condition do you see Hypertrophy of Brunner’s glands?

A

Peptic Ulcer disease

FA - GastroIntestinal (25 decks)

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