G11 Flashcards
What are the Pancreatic enzymes?
a-amylase Lipase Phospholipase A Colipase Proteases (trypsin, chymotrypsin, elastase, carboxypeptidases) Trypsinogen
a-amylase function.
Starch digestion
*Secreted in active form
What pancreatic enzymes are involved in fat digestion?
Lipase
Phospholipase A
Colipase
What are pancreatic proteases secreted as?
Proenzymes (AKA zymogens)
How is trypsinogen converted to trypsin?
Enterokinase/Enteropeptidase
Where are Enterokinase/Enteropeptidase enzymes secreted from?
Duodenal mucosa
What are the enzymes involved in Carbohydrate digestion?
Salivary amylase
Pancreatic amylase
Oligosaccharide hydrolases
Salivary amylase.
Starts digestion
Hydrolyzes a-1,4 linkages to yield disaccharides (maltose and a-limit dextrins)
Pancreatic amylase.
Highest concentration in Duodenal lumen
Hydrolyzes starch to oligosaccharides and disaccharides
Oligosaccharid hydrolases.
Brush border of intestines
Rate-limiting step in carb digestion
Produce monosaccharides from oligo- and disaccharides
Only ______________ are absorbed by enterocytes.
Monosaccharides
- glucose
- galactose
- fructose
In the enterocytes, Glucose and Galactose are taken up by what?
SGLT1 (Na+ dependent)
In the enterocytes, how is Fructose taken up?
Facilitated diffusion by GLUT-5
How are monosaccharides transported to the blood?
GLUT-2
What is the function of the D-xylose absorption test?
Distinguishes GI mucosal damage from other causes of malabsorption
