GI and autoimmune Flashcards
gut associated lymphoid tissue GALT
located in
lamina propria
intraepithelial lymphocytes
Mesenteric lymph nodes
Peyer patches
Isolated, lymphoid, follicles
Helps defend against external factors that penetrate the luminal mechanical barrier
Galt organs
tonsils
Peyer’s patches
Appendix
colon
Cecum
having one auto immune disease…
triples your risk of getting another
Genetic component with environmental trigger
Incidence and woman 78%
Incidence has tripled in the last 50 years
Sjogren’s disease
swollen, salivary glands- parotids
Dry eyes
Dry mouth
Dry nasal passages
Dry skin rashes
Vagina dryness
Fatigue joint pain
malabsorption disorder’s
Lactase deficiency
Celiac sprue
Lactase deficiency
milk intolerance
Diarrhea
Floating due to fermentation of lactose in the colon
Celiac sprue
malabsorption syndrome
hypersensitivity to wheat gluten gliadin
Resulting in immune mediated destruction of villi
immune disorders affecting the liver and gallbladder
auto immune hepatitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Autoimmune hepatitis
occurs in young woman
Associated with other auto immune diseases
Antibodies in serum
Primary biliary cirrhosis
occurs in middle-aged woman
Chronic jaundice
Hyper cholesterolemia
Antibodies in serum
primary sclerosing cholangitis
Occurs in men younger than 40
Associated with ulcerative colitis
no specific antibodies
Inflammatory bowel disease
Crohn’s disease
Ulcerative colitis
Recurrent intestinal inflammation
Crohn’s disease and ulcerative colitis
Immunological component
Chronic and unpredictable course
Third a decade of life, 20 to 30 years
Unknown cause
promote healthy immune
Improve fluid intake
Well balanced diet
Increase antioxidant and protein intake
Adequate sleep
Avoid caffeine and sugar
Reduce stress
Spend time outdoors
vitamin D levels checked
limit chemical exposure
avoid fragrances
Probiotics
Pre-biotics fermented food
low grain, no grain, gluten-free diets
