GI Flashcards

1
Q

Main functions of the GIT

A

ingestion
Mastication
Deglutition
Digestion
absorption
Excretion

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2
Q

Clinical manifestations of disease

A

nausea
Vomiting
Anorexia cachexia
Constipation
Dysphagia
achalasia
Heartburn
G.I. bleeding
Abdominal pain

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3
Q

nausea

A

Strong emotions
MI
diabetic acidosis
Ménière’s disease
hepatobiliary
pancreatic

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4
Q

Vomiting

A

electrolyte and fluid imbalance
pulmonary aspiration
Esophagus rupture

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5
Q

Diarrhea

A

Acidosis from bicarbonate depletion

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6
Q

anorexia cachexia

A

Increase metabolic rate due to tumor cells

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7
Q

Abdominal pain

A

Mechanical pain stretching
inflammatory pain

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8
Q

Achalasia

A

Reported feeling of fullness as LES fails to relax

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9
Q

aging of the GIT

A

changes begin before age 50 or earlier

Oral changes, altered tooth decay, taste buds, decreased salivation

Dysmotility and emptying

Slow absorption of nutrients

B12 deficiency

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10
Q

main exocrine and endocrine

A

salivary glands
Stomach
Small intestine

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11
Q

Salivary glands

A

amylase- digestion of starch

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12
Q

stomach

A

Pepsin- digestion of proteins
Gastrin- released from the pyloric glandular cells- simulates the production of HCl in stomach
intrinsic factor - produced by parietal cells, absorption of vitamin B 12

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13
Q

Small intestine

A

enterokinase- Activates pancreatic enzymes
cholecystokinin- gallbladder contraction + pancreatic secretion of bicarbonates
secretin- stimulates the creation of Trypsin and chymotrypsin

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14
Q

three divisions of the GIT

A

Upper middle lower

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15
Q

Upper division

A

mouth esophagus stomach
Initial digestion

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16
Q

middle division

A

Small intestine
Most digestion and absorption

17
Q

lower division

A

Large intestines
Absorption storage and elimination

18
Q

four layers of the wall of the GIT

A

Mucosa
Submucosa
Muscularis externa
Serosa

19
Q

mucosa

A

interlining faces the lumen

Mucosal epithelium
Lamina propria connective tissue
Muscularis Mucosa

20
Q

Submucosa

A

Submucosal plexus
Blood vessels
Lymph vessels, lymphoid tissue, Peyer’s patches
Enteric nervous system Meissner’s plexus

21
Q

muscularis extrernus

A

smooth muscle

Inner circular layer

Myenteric plexus sandwiched between these layers

Outer longitudinal layer

22
Q

Serosa

A

Connective tissue
Continuation of peritoneum
Forms folds called mesentery

23
Q

cells of mouth to esophagus

A

Squamous

24
Q

cells of stomach to anus

A

Cuboidal glandular
Squamous at the end

25
Q

supradiaphragmatic muscularis cover

A

Adventitia

26
Q

infradiaphragmatic, muscularis cover

A

Peritoneum

27
Q

mucosa layer

A

rugae
plicae
villi
invaginations

28
Q

accessory organs

A

liver
gallbaldder
Pancreas

29
Q

Liver

A

carb/lipid/protein metabolism
Glycogen and vitamin storage
Bile production
Waste product, hormonal and drug removal

30
Q

pancreas

A

Pancreatic alpha amylase
lipase
Nuclease proteases