GI - 6 Diarrhea pt 3 Flashcards

1
Q

What is Whipple’s disease?

A

a bacterial disease that can cause malabsorption

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2
Q

2 imaging tests that are Sensitive for the diagnosis of chronic pancreatitis and pancreatic cancer

A

Abdominal CT and endoscopic ultrasonography

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3
Q

What is Useful in patients with bile salt-induced diarrhea secondary to intestinal resection or ileal disease?

A

Cholestyramine

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4
Q

Fats are broken down by ____ to monoglycerides and fatty acids that form micelles with bile salts

A

pancreatic lipase

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5
Q

Proteins are hydrolyzed by ___ to di- and tripeptides and amino acids

A

pancreatic proteases

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6
Q

Name 4 fat soluble vitamins. What can happen?

A

A,D,E,K. If malabsorbed, causes bleeding, osteoporosis, and hypocalcemia

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7
Q

Insufficient intraluminal concentrations of pancreatic enzymes or bile salts

A

Impaired intraluminal digestion

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8
Q

What is Impaired intraluminal digestion?

A

Insufficient intraluminal concentrations of pancreatic enzymes or bile salts

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9
Q

large, greasy, foul-smelling stools are signs of what diarrhea disease?

A

Steatorrhea

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10
Q

Wt loss, gaseous distention and flatulence, Steatorrhea are symptoms of

A

Pancreatic insufficiency (causing impaired digestion)

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11
Q

Malabsorption of specific nutrients may occur as a result of deficiency in an isolated brush border enzyme. What Phase? What enzyme deficiency is caused by this?

A

Mucosal phase. Lactase deficiency

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12
Q

What phase? Obstruction of the lymphatic system results in impaired absorption of chylomicrons and lipoproteins
Steatorrhea and significant enteric protein losses or “protein-losing enteropathy”

A

Absorptive phase

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13
Q

Permanent dietary disorder caused by an immunologic response to __

A

gluten

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14
Q

Celiac disease is 100X more present in whom?

A

Whites of North Europe ancestry

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15
Q

“Classic” symptoms of malabsorption (of celiac disease) includes:

A

including diarrhea, steatorrhea, weight loss, abdominal distention, weakness, muscle wasting, or growth retardation

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16
Q

Physical examination
May be normal in mild cases
May reveal signs of malabsorption

A

Celiac disease

17
Q

Cutaneous variant of celiac disease
Characteristic skin rash consisting of pruritic papulovesicles over the extensor surfaces of the extremities and over the trunk, scalp, and neck

A

Dermatitis herpetiformis

18
Q

Limited proximal involvement anemia involves what problems?

A

Iron deficiency

19
Q

More extensive anemia involves

A

Vit B deficiency

20
Q

prothrombin time tests for:

A

Fat soluble vitamin absorption

21
Q

Which patients get tests for celiac disease?

A

Anyone whom there is a suspicion of celiac disease