GI 10 - Irritable Bowel Syndrome Flashcards
__ is a diagnosis of exclusion. Once you’ve excluded everything else, it’s this.
Irritable Bowel Syndrome
Combination of chronic (>3 months) lower abdominal symptoms and bowel complaints
IBS
Abdominal discomfort or pain that has 2 of these features:
(1) relieved with defecation or
(2) onset associated with a change in frequency of stool, or
(3) onset associated with a change in form (appearance) of stool
IBS
more sensitive to gas pressures. They’ll feel their rectum is full and need to go to the bathroom when there’s less than normal
Visceral Hypersensetivity
Psychosocial Abnormalities, Abnormal Motility, Visceral Hypersensetivity, Post enteric Infection, Altered Gut Flora
are Pathogenesis of:
IBS
The term for: Variety of abnormal myoelectrical and motor abnormalities have been identified in the colon and small intestine
Abnormal motility
Chronic condition
Typical onset: late teens to twenties
2/3 with IBS are women
Present for at least 3 months before the diagnosis can be considered
IBS
Irritable bowel shouldn’t bother them during the night, that’s more likely ___
Inflammatory bowel syndrome
Treatment of IBS
diet and lifestyle changes
Antispasmotics are also known as
Anticholinergics
If patients have IBS and don’t respond to diet and lifestyle changes, use what type of medications? 3 actual examples.
Anticholinergics aka Antispasmotics
- Hyoscyamine
- Dicyclomine
- Clindinium
Patient has tried diet, lifestyle changes, and antispasmotics and still doesn’t feel better! What do you do now that everything else hasn’t worked? Why is this used last?
Amitriptyline - it’s an antidepressant, but it helps the visceral sensitivity.