GI - 5 Liver Disease pt 3 Flashcards
Ppl with a chronic liver disease like Hep C – will be vaccinated for Hep _ and _.
Hep A and B
2 preventions for Hep B, and who gets them:
- HBIG: Protective or attenuate severity of illness if given in large doses within 7 days if exposure and followed by vaccine
- Vaccinate: Dialysis workers and patients, transfusion patients, spouses and newborns of HBsAg + patients, IVDU, health care workers
NOW: Universal vaccination of infants and children
Post immunization titers checked, lasts 15yrs
You get liver disease and decompensate quickly
Acute Hepatic Failure
most common cause of Acute hepatic failure
Acetaminophen toxicity - suicide attempts or unintentional overdoses
the answer to a viral question I don’t know, or a pediatric question is going to be:
Parvovirus B 19
How has the # of cases of Viral Hepatitis changed over the years?
Declined from 70% to 12% because of Hep B vaccine
What is chronic Hepatitis?
Chronic necrosis and inflammation of the liver for more than 6 months duration
Abnormal LFTs
Histologic findings
Impaired copper metabolism is known as __ disease
Wilson’s disease
What’s Wilson’s disease?
impaired copper metabolism
What causes liver disease, emphysema in lungs
Alpha 1 antitrypsin disease
If someone has chronic Hep B check for Hep _.
Hep E
What is a lab feature of Chronic HBV?
ALT > AST
What’s the med for Chronic HBV? What’s wrong with it though?
Interferon. Not well tolerated, can lead to depression.
inflammation of liver due to fat deposition in the liver
Steatohepatitis
3 clinical findings of chronic HCV?
Fatigue is the most common symptom
Jaundice is rare
Similar to chronic Hep B (hbv)