GI - 5 Liver Disease pt 1

Question 1

Which types of Hepatitis are DNA? RNA?

Answer 1

All Hep’s besides B are RNA viruses. B is a DNA virus

Question 2

Fecal-oral
Increased by crowding and poor sanitation
Contaminated water/food including undercooked shell fish
Excreted in feces for 2 weeks before clinical illness
No chronic carrier state

Answer 2

Hep A

Question 3

It’s acute and goes away. Not chronic.

Answer 3

Hep A

Question 4

Spiking fever is a key sign of

Answer 4

Hep A

Question 5

Dark urine and light stools.
Fatigue, malaise, nausea, vomiting, anorexia
Right upper quadrant pain
Jaundice and hepatomegaly.

Answer 5

Hep A

Question 6

ALT > AST (both are elevated) is a sign of

Answer 6

Hep A, B

Question 7

What are ALT & AST on a lab?

Answer 7

– liver enzymes (amino transferases); will have high levels during liver disease

Question 8

What is GTT on a lab?

Answer 8

lab that determines if high alk phos is from liver or the bone

Question 9

Acute or chronic? Hep A

Answer 9

Acute and goes away in 3 months. Hepatitis A: DOES NOT CAUSE CHRONIC LIVER DISEASE!

Question 10

How can antibody levels identify Hep A?

Answer 10

Excreting in feces is how it’s spread. IgM raises first, then IgG raises second.

Question 11

What’s the only DNA Hep virus?

Answer 11

Hep B

Question 12

1 way Hep B is transmitted is

Answer 12

Heterosexual sex

Question 13

Aninteric means:

Icteric means:

Answer 13

Aninteric - no jaundice

Icteric - jaundice

Question 14

What is the best indicator of Hep B? Why?

Answer 14

Prothrombin time - coagulation proteins are made in the liver. It shows how quickly you can clot.

Question 15

What are LFT’s?

Answer 15

Liver function test. Tests if the liver is working normally or not.

Question 16

The first thing that will appear in the blood when you are sick with Hep B, will persist throughout sickness

Answer 16

Hep B Surface Antigen

Question 17

What is Hep B Surface Antigen?

Answer 17

The first thing that will appear in the blood when you are sick with Hep B, will persist throughout sickness.

Question 18

Having Hep B Surface Antigen for > 4 means:

Answer 18

Chronic Hep B

Question 19

Chronic Hep B is defined as:

Answer 19

having Hep B Surface Antigen in blood for > 4 months

Question 20

What is Anti Hep B surface antigen?

Answer 20

the antigen to HBsAg. Only appears when you have cleared the disease. You don’t have HBsAg anymore. Only Anti HBs.

Question 21

If you’re vaccinated you will have __ in the blood. You won’t have ___ in blood.

Answer 21

you will have Anti HBs

you won’t have HBsAg

Question 22

Why should you test for Hep B core antibody when testing for Hep B?

Answer 22

It fills the window period between HBsAg and Anti HBs.

Question 23

Having what in blood means you were vaccinated for Hep B?

Answer 23

IgG

Question 24

What is found in the blood in only only in very infectious/unlucky cases of Hep B? Indicates viral replication and infectivity

Answer 24

HBeAg - Hep B ‘E’ Antigen