GI 4 Flashcards
true or false - the pancreas is both a endocrine and exocrine gland
true
the exocrine pancreas secretes… while the endocrine pancreas secretes….
HCO3 and hormones
where does the endocrine secretion occur
across the epithelial basolateral surface for diffusion into blood
the main pancreatic duct joins _____ before entering the duodenum
common bile duct
what does the pancreatic juices contain
isotonic alkaline
electrolytes
digestive enzymes
digestive enzymes are secreted by what type of cells
acinar cells
what do amylolytic enzymes do
digest starch into sugars
_____ cleaves trypsinogen to trypsin
enterokinase
where is the enterokinase located
embedded in the luminal membrane
trypsin activates which four inactive enzymes
chymotrypsinogen, pro-elastase, pro-carboxy peptidase A and B and prephospholipase A2
what is the name of the enzyme that hydrolyzes bonds at the C-terminal end
carboxypeptidase A and B
circulating secretin from the small intestine stimulates what …
pancreas and liver
which phase of pancreatic secretion has to do with regulation
intestinal phase
define alkaline tide
after a big meal… parietal cells in stomach produce lots of acid -> large amounts of HCO3 are pumped into the blood
define acid tide
after a big meal… duct cells in the pancreas produce lots of HCO3 -> large amounts of H ions are pumped into the blood
