GI Flashcards

1
Q

Most promising treatment for GALD

A

In utero IVIG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Site of maximal B12 absorption

A

Ileum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Intestine -> Antibacterial substance that interacts preferentially with phospholipids in microbial cell membranes leading to lysis is

A

Alpha defensin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Most common malformation in syndromic or complex CHD

A

Cardiac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Complication of metoclopramine neonates

A

Neuromuscular dystonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Most likely inheritance pattern of GALD

A

Maternal alloimmune disorder affecting the fetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Genetic causes of TEA are found in x percent of cases with established links to multiple syndromes

A

6-10 percent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ELBW Cochrane review on time to reach full feeds comparing intermittent and continuous gastric feeding

A

No difference

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which practice has been associated with centers that have higher survival of patients with CDH

A

Permissive hypercapnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In the case of an anterior anus in a female, the fistula opening is most likely located in the x

A

Perineal body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What urine test may indicate severe NEC if high?

A

Intestinal fatty acid binding protein I FABP. Think fodmap diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Does the fetal intestine respond more or less robustly to bacterial components like lps?

A

More

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

GALD- organ most spared from iron deposition

A

Spleen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Hormone most important for regulation of intestinal transit in the process of intestinal adaptation is

A

Glucagon like peptide 2 We’re moving and this requires sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which surgical approach is the preferred one for separating the Gi tract from the reproductive and urinary tracts ?

A

Posterior Sagittal approach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

GI motility - older versus preterm neonates phasic activity

A

Preterm - clusters of low amplitude non propagating pressure waves during phase three (fasting)
Term- regular phasic propagating activity as one of the phases of phase three

17
Q

Which contaminant in probiotics has caused NEC and death?

18
Q

What gene is involved in alagille ?

A

JAGGED 1 alligator has jagged teeth

19
Q

A decrease in colonization of what bacteria has been observed in stool samples of preterm neonates who later develop NEC ?

A

Firmicutes Want to be cute

20
Q

CDH is a prominent feature of what syndrome ?

A

Fryns - Michelle, lets be friends

21
Q

What can help fecal in continence in people with anorectal malformations?

A

Comprehensive bowel regimens

22
Q

Which elements should be reduced in TPN in a patient with cholestasis ?

A

Manganese and copper

23
Q

The primary substrate used by enterocytes in the process of intestinal adaptation

A

Glutamine gluttonous glutamine

24
Q

What is a valid marker of CDH severity on US?

A

Lung to head ratio on the contralateral area of the two dimensional lung to head circumference measured with US (22-26 weeks)

25
Is an esophagram necessary post EA repair ?
No. Not mandatory before initiation of feedings. And omission rarely influences clinical management
26
What to do after birth on patient with omphalocele?
Protect it with saline soaked dressing and place in a bowel bag
27
Risk factors for gastroschisis
Maternal smoking, young age, alcohol use, illicit substance use, use of over the counter vaso active meds and multiple genes implicated
28
Which protein predictive marker is decreased in a patient who has NEC ?
Inter alpha inhibitor protein
29
What study can diagnose intestinal strictures post NEC ?
Contrast study
30
What mode of delivery is generally advocated for in giant omphaloceles ?
C section
31
GALD occurs after x weeks of gestation, concurrent with the onset of active trans placental immunoglobulin x transfer which starts at x weeks gestation
18 G 12
32
Gastroschisis is associated with preterm birth in x percent of cases
30 percent
33
Is GALD A spectrum?
Yes. Could have liver disease without extra hepatic siderosis
34
Best serum marker reflective of enterocyte maturation in intestinal adaptation is what amino acid
Citrulline your intestine better mature after being sprayed with citrus!
35
Two species most associated with Dec NEC in probiotics
Lactobacillus and bifidobacterium