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Neonatology boards > GI > Flashcards

GI Flashcards

1
Q

Most promising treatment for GALD

A

In utero IVIG

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2
Q

Site of maximal B12 absorption

A

Ileum

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3
Q

Intestine -> Antibacterial substance that interacts preferentially with phospholipids in microbial cell membranes leading to lysis is

A

Alpha defensin

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4
Q

Most common malformation in syndromic or complex CHD

A

Cardiac

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5
Q

Complication of metoclopramine neonates

A

Neuromuscular dystonia

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6
Q

Most likely inheritance pattern of GALD

A

Maternal alloimmune disorder affecting the fetus

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7
Q

Genetic causes of TEA are found in x percent of cases with established links to multiple syndromes

A

6-10 percent

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8
Q

ELBW Cochrane review on time to reach full feeds comparing intermittent and continuous gastric feeding

A

No difference

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9
Q

Which practice has been associated with centers that have higher survival of patients with CDH

A

Permissive hypercapnia

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10
Q

In the case of an anterior anus in a female, the fistula opening is most likely located in the x

A

Perineal body

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11
Q

What urine test may indicate severe NEC if high?

A

Intestinal fatty acid binding protein I FABP. Think fodmap diet

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12
Q

Does the fetal intestine respond more or less robustly to bacterial components like lps?

A

More

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13
Q

GALD- organ most spared from iron deposition

A

Spleen

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14
Q

Hormone most important for regulation of intestinal transit in the process of intestinal adaptation is

A

Glucagon like peptide 2 We’re moving and this requires sugar

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15
Q

Which surgical approach is the preferred one for separating the Gi tract from the reproductive and urinary tracts ?

A

Posterior Sagittal approach

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16
Q

GI motility - older versus preterm neonates phasic activity

A

Preterm - clusters of low amplitude non propagating pressure waves during phase three (fasting)
Term- regular phasic propagating activity as one of the phases of phase three

17
Q

Which contaminant in probiotics has caused NEC and death?

A

Rhizopus

18
Q

What gene is involved in alagille ?

A

JAGGED 1 alligator has jagged teeth

19
Q

A decrease in colonization of what bacteria has been observed in stool samples of preterm neonates who later develop NEC ?

A

Firmicutes Want to be cute

20
Q

CDH is a prominent feature of what syndrome ?

A

Fryns - Michelle, lets be friends

21
Q

What can help fecal in continence in people with anorectal malformations?

A

Comprehensive bowel regimens

22
Q

Which elements should be reduced in TPN in a patient with cholestasis ?

A

Manganese and copper

23
Q

The primary substrate used by enterocytes in the process of intestinal adaptation

A

Glutamine gluttonous glutamine

24
Q

What is a valid marker of CDH severity on US?

A

Lung to head ratio on the contralateral area of the two dimensional lung to head circumference measured with US (22-26 weeks)

25
Q

Is an esophagram necessary post EA repair ?

A

No. Not mandatory before initiation of feedings. And omission rarely influences clinical management

26
Q

What to do after birth on patient with omphalocele?

A

Protect it with saline soaked dressing and place in a bowel bag

27
Q

Risk factors for gastroschisis

A

Maternal smoking, young age, alcohol use, illicit substance use, use of over the counter vaso active meds and multiple genes implicated

28
Q

Which protein predictive marker is decreased in a patient who has NEC ?

A

Inter alpha inhibitor protein

29
Q

What study can diagnose intestinal strictures post NEC ?

A

Contrast study

30
Q

What mode of delivery is generally advocated for in giant omphaloceles ?

A

C section

31
Q

GALD occurs after x weeks of gestation, concurrent with the onset of active trans placental immunoglobulin x transfer which starts at x weeks gestation

A

18
G
12

32
Q

Gastroschisis is associated with preterm birth in x percent of cases

A

30 percent

33
Q

Is GALD A spectrum?

A

Yes. Could have liver disease without extra hepatic siderosis

34
Q

Best serum marker reflective of enterocyte maturation in intestinal adaptation is what amino acid

A

Citrulline your intestine better mature after being sprayed with citrus!

35
Q

Two species most associated with Dec NEC in probiotics

A

Lactobacillus and bifidobacterium

Neonatology boards (18 decks)

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