Fen Flashcards
Peak vacuum during a neonatal suck is created with lowering of
Tongue
Excessive amount of what trace element can lead to basal ganglia injury?
Manganese in the ganglia
Amino acid considered semi essential and needed in synthesis of antioxidant glutathione
Cysteine, hollenbeck overweight from gluttony
Folates are required in the degradation of
Methionine
Estimated survival time for 2 kg baby without external nutrients
10 days
Most common cause of decreased milk supply in moms of premies is
Progestin based contraception
Maternal demographic most related to not breastfeeding
Low income
Milk donors undergo serologic screening for which infections
Hepatitis B, C, syphilis, HIV, human lymphotropic virus
Nutritional goal intake of copperin premie
120 microgram per kilogram perday. To scale copper mountain you have to put in 120%
Predominant storage site for zinc is?
Bone
Zinc nutritional goal for premies
350 micrograms per kilo per day
Pasteurization of donor milk eliminated which two viruses that they later test the milks for
HIV and CMV
Which outcome is decreased with lactoferrin supplementation?
Late onset sepsis
Stock TPN for premies has at least x grams per 80 mL of amino acids
3
Pasteurization may decrease the amount and activity of what important enzyme in milk
Lysozyme pasteurization is like using Lysol
The increase in PTH on the 1st day after birth can be blunted by infusion of what
Calcium
Lipid solutions containing omega x fatty acids as opposed to omega x aa can minimize liver disease
3
6
Do current IV and enteral nutritional approaches for long chain PU fatty acids reach intrauterine accretion rates ?
No
Component in human milk most attributed to decrease NEC is
Platelet activating factor acetylhydrolase
Nonnutritive sucking ratio
6:1 to 8:1
Most likely mechanism by which lactoferrin protects neonates from infection
Antibiotic effect after proteolysis to lactoferricin
How and where does most phosphorus absorption occur ?
Active and passive transport in the jejunum. PH and PH and J and J
Most typical manifestation of zinc deficiency
Perianal dermatitis
The cord blood [magnesium] is x compared to maternal [] reflecting what type of transport ?
Higher
Active placental transport
Is there a risk of indirect hyperbili with free fatty acid delivery?
A theoretical one, yes. Actual risk is minimal. Fatty acids compete for albumin binding sites but molar ratios of 4:1 to 5:1 of free fatty acids to albumin are required for significant changes in bili binding
In growing preterm neonates, the percentage of intestinal absorption of calcium is between x percent of intake
50-60 percent
Zinc absorption in gut is enhanced by intake of what
Protein - prozeinc
What type of anemia is associated with copper deficiency ?
Hypochromic
Major LCPUFA in the retina necessary for phototransduction is
Docosahexaenoic acid 22:6, n-3
Lactoferrin binds to which 4 things ?
Ferric iron, ribonuclease, nucleotide, heparin
Can fish oil based emulsions achieve similar docohexaenoic acid levels to other non fish oil emulsions?
Yes, higher !
What percentage of neonates less than 1.5 kg get rickets or fractures ?<1kg?
10-30 percent
50-60 percent
Dietary component with highest amount of lactoferrin
Colostrum
LCPUFA improves what outcome ?
Visual acuity
Suppression of pathogenic organisms by commensal organisms in breast milk is done by suppression of Transcription factor nuclear factor kappa beta ( Anti inflammatory effect) when the commensural organism binds to what
Toll like receptor
The upper threshold for peripherally infused PPN osnolarity is…
1000 mOsm per liter
Lipoprotein lipase is present primarily in what tissue type?
Adipose tissue
Copper absorption is impaired by uptake of what
Ascorbic acid
The biologically active component of human milk most preserved after initial freezing and pasteurization is what
Linoleic acid Linoleum very sturdy
Most likely cause of hypokalemia in ELBW in first three days
Shift of potassium from intracellular to extra cellular fluid
Premie moms have less milk why?
Not because of gestation! It’s insufficient monitoring of volumes, lack of info and equipment, lack of on site storage, stress of nicu
The nutrient most likely to reduce oxidative stress through its interaction with the antioxidant glutathione peroxidase is
Selenium
