2022 NeoReviews

Question 1

Findings of macrocephaly, split sutures, and thumb adduction in a male infant suggest what diagnosis ?

Answer 1

X linked hydrocephalus

Question 2

Next best diagnostic step for baby who may have osteomyelitis is…

Answer 2

Ultrasound of joint

Question 3

CCHD screening has low sensitivity for the detection of which 4 heart lesions?

Answer 3

Interrupted aortic arch, coarctation of the aorta, double outlet RV, ebstein anomaly

Question 4

The presence of bone stippling and cataracts in newborn with skeletal dysplasia points to what dx?

Answer 4

Zellweger syndrome

Question 5

When concerned for congenital cutaneous candidiasis, co- treat for … and so the empiric therapy is?

Answer 5

Staph
Amphotericin B, nafcillin, gentamicin

Question 6

PTPN11 pathogenic variant is associated with what syndrome ?

Answer 6

Noonan (have inc nuchal translucency)

Question 7

IUGR at risk for chronic (what organ) disease ?

Answer 7

Kidney

Question 8

If a baby’s only manifestation of congenital CMV is sensorineural HL do you treat ?

Answer 8

No
Serial hearing exams

Question 9

Hemolysis can occur with NEC due to activation of what antigen?

Answer 9

T antigen

Question 10

Shoulder adduction with PICC in what vein will have catheter tip move outward ?

Answer 10

Cephalic (outward) and basilic (inward). Alphabetic

Question 11

The risk of a coexisting hepatic hemangioma is increased with the presence of how many infantile hemangiomas ?

Answer 11

5 or more US their liver

Question 12

First step for managing congenital nasal pyriform aperture stenosis ?

Answer 12

Conservative like steroids

Question 13

Recommendation for hep B if you’re born at less than 2kg?

Answer 13

At 30 days of life or discharge , whichever is first

Question 14

After resection of a thoracic teratoma, how do you monitor for recurrence or metastatic spread ?

Answer 14

Serial serum AFP

Question 15

Infants with surfactant protein B deficiency usually die without …

Answer 15

Lung transplant (with it , 5 year survival is >50 percent)

Question 16

Blood group inheritance phenotypes are

Answer 16

A, B,AB, O
Square would be at top - A,B, O and same at the sides. Each gets two alleles - O is recessive so need TWO alleles to be O

Question 17

t18 -> those who survive the first year are likely to survive to age …

Answer 17

5 years

Question 18

What makes you a low risk BRUE? Can be observed in ED

Answer 18

Older than 60 days, born >32 weeks, only one BRUE, lasts <1 min, no official CPR, no concerning hx, physical findings

Question 19

Blunting of top flow Column on ventilator suggests what is not long enough?

Answer 19

I time

Question 20

What is the dx when Serial measurements show increasingly elevated TSH and hypothyroxinemia and what to do?

Answer 20

Congenital hypothyroid
Levo

Question 21

Maternal treatment with what has the highest chance of preventing ICH in a fetus with NAIT?

Answer 21

IVIG

Question 22

Strategies to reduce conductive heat loss include

Answer 22

Warm blanket
Chemical mattress

Question 23

? Has high sensitivity and specificity as a marker for BA in infants older than 30 days

Answer 23

Matrix metalloproteinase-7

Question 24

What may ameliorate liver injury and therefore symptoms in patient with zellweger syndrome?

Answer 24

Cholic acid (give back bile acids )

Question 25

NRP PRE birth questions (4)

Answer 25

GA color amniotic fluid Risk factors Umbilical cord management

Question 26

Calculation of partial exchange (total blood volume to be exchanged to achieve a goal crit of 55)

Answer 26

(Total blood volume mL x observed CRIT - desired crit) / observed crit Of note, TBV is 80 per kilo

Question 27

HFOV -> frequency is related to TV HOW?

Answer 27

Inversely

Question 28

When do eyelids begin to separate after being fused ?

Answer 28

Week 22 and takes 3-6 weeks in utero to complete. If born takes 5 days

Question 29

Neonatal Graves’ disease is mediated by antibodies to …

Answer 29

Thyroid stimulating hormone receptor antibodies (TRab) baby would be hyperthyroid

Question 30

Poisseulles law How does resistance affect mean airway pressure ?

Answer 30

Resistance = length of tube/ radius ^4 Higher resistance, lower MAP

Question 31

Milrinone- what type of med? How does it increase cardiac output?

Answer 31

Phosphodiesterase 3 inhibitor Inc myocardial stroke volume by better diastolic relaxation = lucitropy

Question 32

Primary mechanism for anti inflammatory effect of CLD of glucocorticoids?

Answer 32

Genomic mechanisms

Question 33

Half life of nadolol?

Answer 33

Five days

Question 34

When to give rotavirus

Answer 34

6-15 weeks after birth , 2-3 doses, Finished by 8 months old

Question 35

What virus can manifest with diarrhea, ileus, meningitis, seizures and apnea ?

Answer 35

Parecho virus

Question 36

First step in finding etiology of congenital nephrotic syndrome (proteinuria, swelling, large kidneys)

Answer 36

Genetic testing

Question 37

Best way to estimate ETT depth

Answer 37

GA nomogram

Question 38

When to consider methemoglobinemia?

Answer 38

Cyanosis unresponsive to O2 and chocolate blood when exposed to air

Question 39

Third trimester fetal protein accretion ?

Answer 39

4 g per kilo per day

Question 40

? Mediated Brady is common side effect of precedex?

Answer 40

Baro receptor mediated reflex Brady

Question 41

If discharged with hx stage 1 AKI what is appropriate follow up?

Answer 41

Cr in three months

Question 42

Rocuronium is an acetylcholine? And sugammadex? Paralysis without associated ? Effects

Answer 42

Antagonist Reverses Muscarinic (Brady and bronchospasm)

Question 43

During an evacuation for disaster, first step is ?

Answer 43

Assigning incident commander

Question 44

Encephalopathy on exam of a patient with SGH is a key predictor of early ?

Answer 44

Mortality