2020 NeoReviews

Question 1

Anticoagulant effects of heparin are mediated through activation of

Answer 1

Anti thrombin (which is lower in neonates )

Question 2

Women with active syphillis may have false… nontreponemal serologic sereen

Answer 2

Negative

Question 3

Presence of … or … encephalopathy is a determining criterion for use of therapeutic hypothermia

Answer 3

Moderate or severe

Question 4

Prader willi is related to genetic… most common genetic abnormality is…

Answer 4

Imprinting. Microdeletion

Question 5

Mothers with poorly controlled diabetes can have significant… depletion from chronic urinary loses

Answer 5

Magnesium and calcium

Question 6

Up to 25% of individuals with situs inversus have…

Answer 6

Primary ciliary dyskinesia

Question 7

What does a positive granulocyte agglutination test mean?

Answer 7

Presence of antineutrophil antibodies (immune mediated cause for neonatal neutropenia)

Question 8

What syndrome has short and mildly curved fingers, short stature, metaphyseal dysplasia, sparse and fine hair, and immune deficiency +|- hirschprungs?

Answer 8

Cartilage - hair hypoplasia

Question 9

ARPCKD: enlarged kidneys and congenital … fibrosis

Answer 9

Hepatic

Question 10

Calculation of dose of vials of anti RhD immunoglobulin to prevent maternal alloimmunization after exposure to fetal red blood cells ?

Answer 10

Vials (300 ug is one)= fetal blood (mL)/30mL + 1

Question 11

When is the optimal time to measure thyroid stimulating hormone and free thyroxine in the neonate at risk for hyperthyroidism?

Answer 11

Between 3 and 5 days of age

Question 12

The most common cause of severe thrombocytopenia in a healthy appearing neonate is …

Answer 12

Neonatal alloimmune thrombocytopenia (NAIT)

Question 13

If preterm, what is best next step for a BPP of 6/10?

Answer 13

Repeat testing in 6-24 hours. If term, would deliver.

Question 14

Triad of congenital cataracts, Severe hypotonia, male neonate with family hx severe renal dz:

Answer 14

Oculocerebrorenal syndrome (Lowe syndrome). Mutation in OCRL.

Question 15

Is nonpenicillin considered adequate treatment for syphilis during pregnancy? What are the implications tor the infant?

Answer 15

No.it is considered inadequately treated. Infant will need iv or Im penicillin before discharge

Question 16

When would a preterm infant usually present with symptomatic postnatal acquired CMV?

Answer 16

35-60 days of life

Question 17

… is the leading cause of preventable developmental disabilities in the world

Answer 17

Chronic alcohol use during pregnancy

Question 18

Arrest of lung development in the … stage of lung development is the hallmark of BPD

Answer 18

Cannalicular

Question 19

Hyponatremia leads to poor growth by inhibiting function of the… antiporter

Answer 19

Sodium / hydrogen Na+/H+

Question 20

During a fetal maternal hemorrhage, What is the calculation for fetal whole blood using maternal blood volume and % fetal blood cells?

Answer 20

Fetal whole blood (mL)= (% fetal blood cells) x 5000 ml

Question 21

What is the primary mechanism of action of caffeine citrate?

Answer 21

Competitive antagonism of adenosine receptors

Question 22

The half life of caffeine … with post natal age, resulting in … serum drug [] at the same dose

Answer 22

Decreases. Lower.

Question 23

What thyroid issue can occur as a complication of a large infantile hemangioma?

Answer 23

Consumptive hypothyroidism

Question 24

Subcutaneous fat necrosis occurs at a median of… days after birth and can be associated with what electrolyte anomaly?

Answer 24

6. Hypercalcemia.

Question 25

Irradiation of blood components decreased the risk of…

Answer 25

Transfusion associated graft versus host disease

Question 26

Is breast feeding recommended for women in medication assisted opioid addiction programs?

Answer 26

Yes

Question 27

Natal teeth are usually what type of tooth?

Answer 27

Early emotion of the primary teeth, rather than a super numerary tooth. Have 2 be within first 30 days

Question 28

Lumbar hernia is a component of lumbocostovertebral syndrome, that can inturn, be a component of…

Answer 28

Diabetic embryopathy

Question 29

Ventral horn lesion can cause … while dorsal horn cause …

Answer 29

Paralysis. Sensory deficits

Question 30

>80% female patients with classic galactosemia will have primary

Answer 30

Ovarian insufficiency

Question 31

Which virus can mimic an acute surgical abdomen?

Answer 31

Human parechovirus3

Question 32

What is the classic triad for renal vein thrombosis?

Answer 32

Gross hematuria, flank mass, and thrombocytopenia

Question 33

Congenital… hernias ave frequently associated with crytoorchidism in male infants.

Answer 33

Spigelian hernia through aponeurosis of transverse abdominis

Question 34

The highest risk to a neonate from directed donation blood is…

Answer 34

Transfusion related graft versus host disease

Question 35

When in preterm labor, mothers with myasthenia graves should not be given…

Answer 35

Magnesium sulfate

Question 36

Topical application of povidone iodine can cause… in extremely premature infants

Answer 36

Transient hypothyroidism

Question 37

What is the most notable electrolyte anomaly after a double volume exchange transfusion?

Answer 37

Hypocalcemia

Question 38

Epidermolysis bullosa simplex is associated with cleavage of the skin at or above the… layer.

Answer 38

Basal cell

Question 39

If a pregnant woman hasn't received MMR, when should she get it?

Answer 39

In the immediate postpartum period before discharge from the hospital

Question 40

Why does epinephrine cause return of spontaneous circulation?

Answer 40

Because of the alpha l effect -> raises systemic vascular resistance and increases blood flow through the coronary arteries during diastole

Question 41

Most post circumcision bleeding can be controlled with …

Answer 41

5-10 minutes of direct pressure and use of an appropriately placed circumferencial pressure dressing

Question 42

What is the best fluid choice to treat a lithium exposed neonate with resulting diabetes insipidus?

Answer 42

Replace urinary water loses with 10% dextrose in water

Question 43

Infants with G6PD deficiency may have a false positive newborn screen for…

Answer 43

Galactosemia

Question 44

What are causes of early onset ( 1-4 days of life) hypocalcemia?

Answer 44

Parathyroid i disturbances, low maternal vitamin D, and calcitonin. IDM increased risk

Question 45

Half life of zero order drug eliminated by zero order kinetics increases with…

Answer 45

Dose

Question 46

What is the most common neuvodevelopmental impairment in extremely preterm infants?

Answer 46

Cognitive delays