2020 NeoReviews Flashcards
Anticoagulant effects of heparin are mediated through activation of
Anti thrombin (which is lower in neonates )
Women with active syphillis may have false… nontreponemal serologic sereen
Negative
Presence of … or … encephalopathy is a determining criterion for use of therapeutic hypothermia
Moderate or severe
Prader willi is related to genetic… most common genetic abnormality is…
Imprinting. Microdeletion
Mothers with poorly controlled diabetes can have significant… depletion from chronic urinary loses
Magnesium and calcium
Up to 25% of individuals with situs inversus have…
Primary ciliary dyskinesia
What does a positive granulocyte agglutination test mean?
Presence of antineutrophil antibodies (immune mediated cause for neonatal neutropenia)
What syndrome has short and mildly curved fingers, short stature, metaphyseal dysplasia, sparse and fine hair, and immune deficiency +|- hirschprungs?
Cartilage - hair hypoplasia
ARPCKD: enlarged kidneys and congenital … fibrosis
Hepatic
Calculation of dose of vials of anti RhD immunoglobulin to prevent maternal alloimmunization after exposure to fetal red blood cells ?
Vials (300 ug is one)= fetal blood (mL)/30mL + 1
When is the optimal time to measure thyroid stimulating hormone and free thyroxine in the neonate at risk for hyperthyroidism?
Between 3 and 5 days of age
The most common cause of severe thrombocytopenia in a healthy appearing neonate is …
Neonatal alloimmune thrombocytopenia (NAIT)
If preterm, what is best next step for a BPP of 6/10?
Repeat testing in 6-24 hours. If term, would deliver.
Triad of congenital cataracts, Severe hypotonia, male neonate with family hx severe renal dz:
Oculocerebrorenal syndrome (Lowe syndrome). Mutation in OCRL.
Is nonpenicillin considered adequate treatment for syphilis during pregnancy? What are the implications tor the infant?
No.it is considered inadequately treated. Infant will need iv or Im penicillin before discharge
When would a preterm infant usually present with symptomatic postnatal acquired CMV?
35-60 days of life
… is the leading cause of preventable developmental disabilities in the world
Chronic alcohol use during pregnancy
Arrest of lung development in the … stage of lung development is the hallmark of BPD
Cannalicular
Hyponatremia leads to poor growth by inhibiting function of the… antiporter
Sodium / hydrogen Na+/H+
During a fetal maternal hemorrhage, What is the calculation for fetal whole blood using maternal blood volume and % fetal blood cells?
Fetal whole blood (mL)= (% fetal blood cells) x 5000 ml
What is the primary mechanism of action of caffeine citrate?
Competitive antagonism of adenosine receptors
The half life of caffeine … with post natal age, resulting in … serum drug [] at the same dose
Decreases. Lower.
What thyroid issue can occur as a complication of a large infantile hemangioma?
Consumptive hypothyroidism
Subcutaneous fat necrosis occurs at a median of… days after birth and can be associated with what electrolyte anomaly?
- Hypercalcemia.
Irradiation of blood components decreased the risk of…
Transfusion associated graft versus host disease
Is breast feeding recommended for women in medication assisted opioid addiction programs?
Yes
Natal teeth are usually what type of tooth?
Early emotion of the primary teeth, rather than a super numerary tooth. Have 2 be within first 30 days
Lumbar hernia is a component of lumbocostovertebral syndrome, that can inturn, be a component of…
Diabetic embryopathy
Ventral horn lesion can cause … while dorsal horn cause …
Paralysis. Sensory deficits
> 80% female patients with classic galactosemia will have primary
Ovarian insufficiency
Which virus can mimic an acute surgical abdomen?
Human parechovirus3
What is the classic triad for renal vein thrombosis?
Gross hematuria, flank mass, and thrombocytopenia
Congenital… hernias ave frequently associated with crytoorchidism in male infants.
Spigelian hernia through aponeurosis of transverse abdominis
The highest risk to a neonate from directed donation blood is…
Transfusion related graft versus host disease
When in preterm labor, mothers with myasthenia graves should not be given…
Magnesium sulfate
Topical application of povidone iodine can cause… in extremely premature infants
Transient hypothyroidism
What is the most notable electrolyte anomaly after a double volume exchange transfusion?
Hypocalcemia
Epidermolysis bullosa simplex is associated with cleavage of the skin at or above the… layer.
Basal cell
If a pregnant woman hasn’t received MMR, when should she get it?
In the immediate postpartum period before discharge from the hospital
Why does epinephrine cause return of spontaneous circulation?
Because of the alpha l effect -> raises systemic vascular resistance and increases blood flow through the coronary arteries during diastole
Most post circumcision bleeding can be controlled with …
5-10 minutes of direct pressure and use of an appropriately placed circumferencial pressure dressing
What is the best fluid choice to treat a lithium exposed neonate with resulting diabetes insipidus?
Replace urinary water loses with 10% dextrose in water
Infants with G6PD deficiency may have a false positive newborn screen for…
Galactosemia
What are causes of early onset ( 1-4 days of life) hypocalcemia?
Parathyroid i disturbances, low maternal vitamin D, and calcitonin. IDM increased risk
Half life of zero order drug eliminated by zero order kinetics increases with…
Dose
What is the most common neuvodevelopmental impairment in extremely preterm infants?
Cognitive delays
