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Neonatology boards > 2020 NeoReviews > Flashcards

2020 NeoReviews Flashcards

1
Q

Anticoagulant effects of heparin are mediated through activation of

A

Anti thrombin (which is lower in neonates )

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2
Q

Women with active syphillis may have false… nontreponemal serologic sereen

A

Negative

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3
Q

Presence of … or … encephalopathy is a determining criterion for use of therapeutic hypothermia

A

Moderate or severe

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4
Q

Prader willi is related to genetic… most common genetic abnormality is…

A

Imprinting. Microdeletion

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5
Q

Mothers with poorly controlled diabetes can have significant… depletion from chronic urinary loses

A

Magnesium and calcium

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6
Q

Up to 25% of individuals with situs inversus have…

A

Primary ciliary dyskinesia

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7
Q

What does a positive granulocyte agglutination test mean?

A

Presence of antineutrophil antibodies (immune mediated cause for neonatal neutropenia)

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8
Q

What syndrome has short and mildly curved fingers, short stature, metaphyseal dysplasia, sparse and fine hair, and immune deficiency +|- hirschprungs?

A

Cartilage - hair hypoplasia

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9
Q

ARPCKD: enlarged kidneys and congenital … fibrosis

A

Hepatic

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10
Q

Calculation of dose of vials of anti RhD immunoglobulin to prevent maternal alloimmunization after exposure to fetal red blood cells ?

A

Vials (300 ug is one)= fetal blood (mL)/30mL + 1

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11
Q

When is the optimal time to measure thyroid stimulating hormone and free thyroxine in the neonate at risk for hyperthyroidism?

A

Between 3 and 5 days of age

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12
Q

The most common cause of severe thrombocytopenia in a healthy appearing neonate is …

A

Neonatal alloimmune thrombocytopenia (NAIT)

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13
Q

If preterm, what is best next step for a BPP of 6/10?

A

Repeat testing in 6-24 hours. If term, would deliver.

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14
Q

Triad of congenital cataracts, Severe hypotonia, male neonate with family hx severe renal dz:

A

Oculocerebrorenal syndrome (Lowe syndrome). Mutation in OCRL.

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15
Q

Is nonpenicillin considered adequate treatment for syphilis during pregnancy? What are the implications tor the infant?

A

No.it is considered inadequately treated. Infant will need iv or Im penicillin before discharge

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16
Q

When would a preterm infant usually present with symptomatic postnatal acquired CMV?

A

35-60 days of life

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17
Q

… is the leading cause of preventable developmental disabilities in the world

A

Chronic alcohol use during pregnancy

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18
Q

Arrest of lung development in the … stage of lung development is the hallmark of BPD

A

Cannalicular

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19
Q

Hyponatremia leads to poor growth by inhibiting function of the… antiporter

A

Sodium / hydrogen Na+/H+

20
Q

During a fetal maternal hemorrhage, What is the calculation for fetal whole blood using maternal blood volume and % fetal blood cells?

A

Fetal whole blood (mL)= (% fetal blood cells) x 5000 ml

21
Q

What is the primary mechanism of action of caffeine citrate?

A

Competitive antagonism of adenosine receptors

22
Q

The half life of caffeine … with post natal age, resulting in … serum drug [] at the same dose

A

Decreases. Lower.

23
Q

What thyroid issue can occur as a complication of a large infantile hemangioma?

A

Consumptive hypothyroidism

24
Q

Subcutaneous fat necrosis occurs at a median of… days after birth and can be associated with what electrolyte anomaly?

A
  1. Hypercalcemia.
25
Q

Irradiation of blood components decreased the risk of…

A

Transfusion associated graft versus host disease

26
Q

Is breast feeding recommended for women in medication assisted opioid addiction programs?

A

Yes

27
Q

Natal teeth are usually what type of tooth?

A

Early emotion of the primary teeth, rather than a super numerary tooth. Have 2 be within first 30 days

28
Q

Lumbar hernia is a component of lumbocostovertebral syndrome, that can inturn, be a component of…

A

Diabetic embryopathy

29
Q

Ventral horn lesion can cause … while dorsal horn cause …

A

Paralysis. Sensory deficits

30
Q

> 80% female patients with classic galactosemia will have primary

A

Ovarian insufficiency

31
Q

Which virus can mimic an acute surgical abdomen?

A

Human parechovirus3

32
Q

What is the classic triad for renal vein thrombosis?

A

Gross hematuria, flank mass, and thrombocytopenia

33
Q

Congenital… hernias ave frequently associated with crytoorchidism in male infants.

A

Spigelian hernia through aponeurosis of transverse abdominis

34
Q

The highest risk to a neonate from directed donation blood is…

A

Transfusion related graft versus host disease

35
Q

When in preterm labor, mothers with myasthenia graves should not be given…

A

Magnesium sulfate

36
Q

Topical application of povidone iodine can cause… in extremely premature infants

A

Transient hypothyroidism

37
Q

What is the most notable electrolyte anomaly after a double volume exchange transfusion?

A

Hypocalcemia

38
Q

Epidermolysis bullosa simplex is associated with cleavage of the skin at or above the… layer.

A

Basal cell

39
Q

If a pregnant woman hasn’t received MMR, when should she get it?

A

In the immediate postpartum period before discharge from the hospital

40
Q

Why does epinephrine cause return of spontaneous circulation?

A

Because of the alpha l effect -> raises systemic vascular resistance and increases blood flow through the coronary arteries during diastole

41
Q

Most post circumcision bleeding can be controlled with …

A

5-10 minutes of direct pressure and use of an appropriately placed circumferencial pressure dressing

42
Q

What is the best fluid choice to treat a lithium exposed neonate with resulting diabetes insipidus?

A

Replace urinary water loses with 10% dextrose in water

43
Q

Infants with G6PD deficiency may have a false positive newborn screen for…

A

Galactosemia

44
Q

What are causes of early onset ( 1-4 days of life) hypocalcemia?

A

Parathyroid i disturbances, low maternal vitamin D, and calcitonin. IDM increased risk

45
Q

Half life of zero order drug eliminated by zero order kinetics increases with…

A

Dose

46
Q

What is the most common neuvodevelopmental impairment in extremely preterm infants?

A

Cognitive delays

Neonatology boards (18 decks)

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