geriatrics Flashcards
which tool identifies medications where the risk outweighs the benefits ?
STOPP tool
which tool alerts doctors to the right treatment to commence in patients with multiple comorbidities
START
4 features of frontotemporal dementia
onset < 65
insidious onset
preserved memory and visuospatial skills
personality change and social conduct problems
what are the macroscopic changes seen in Picks disease
Atrophy of frontal and temporal lobes
what are the microscopic changes seen in Picks disease
Pick bodies
gliosis
neurofibrillary tangles
senile plaques
what is semantic dementia ?
Fluent progressive aphasia. Fluent speech which is empty and conveys little meaning
what are the precipitating factors of Delirium ?
PINCH ME
Pain
Infection
Nutrition
Constipation
Hydration
Medication
Environment
how do you treatment Delirium ( step by step)
Treat underlying cause
Modify environment
Haloperidol 0.5 mg
which medications should be avoided in Lewy body dementia and why
Anti-psychotics ( Haloperidol) as they may lead to irreversible parkinsonism, rigidity , immobility , falls etc
what is the first line investigation for dementia and what does it include ?
FBC, U+E, LFTs, Calcium, glucose, ESR/CRP, TFTs, vitamin B12, Folate
which factors favour delirium over dementia
acute onset
impairment of consciousness
fluctuation of symptoms ( worse at night, periods of normality)
abnormal perception ( illusions + hallucinations)
agitation and fear
delusions
which questionnaire can be used to assess fraility
PRISMA-7
what is the GPCOG tool used for
screening tool for dementia in GP
what is the pathalogical feature seen in lewy body dementia
Alpha-synuclein cytoplasmic inclusions in the substantia nigra, paralimbic and neocortical areas
what medications can be used in the management of Lewy body dementia
Acetylcholinesterase inhibitors ( Donepezil, Rivastigmine) and Memantine ( NDMA receptor antagonist)