anaesthetics Flashcards
how often before surgery should the oral contraceptive be stopped?
4 weeks prior
what is suxamethonium apnoea ? how is it managed
Autosomal dominant mutation, leading to a lack of specific acetylcholistenerase in the plasma which acts to break down suxamethonium which terminates its muscle relaxant effect.
managed with mechanical ventilation and observation in ITU until effects of suxamethonium wear off
what are the two categories of muscle relaxants used in anaesthetics? give examples of each
Depolarising muscle relaxants - suxamethonium
Non depolarising muscle relaxants - atracurium, vecuronium, pancuronium
which anaesthetic agent is best for haemodynamically unstable patients and why?
Ketamine as it preserves blood pressure and does not cause cardio suppression
which anaesthetic is the choice for rapid sequence induction?
sodium thiopentone
what is the complication of excess infusion of sodium chloride?
Hyper-chloraemic acidosis
what is a common complication after surgery involving the bowel ? what are its features? what blood marker should be checked? How is it managed?
Post-operative ileus - reduced bowel peristaltis resulting in pseudo-obstruction.
features :
abdominal distension, pain , nausea and vomiting, inability to flatus
deranged electrolytes
management -
NBM
NG tube if vomiting
IV fluids
total parenteral nutrition
what is the ASA classification?
I : normal healthy, non smoker + minimal alcohol
II : mild systemic : smoker, social alcohol, pregnancy, obesity ( BMI 30-40) , Well controlled DM/ HTN, mild lung disease
III : severe systemic illness : substantive functional limitations - poorly controlled DM, HTN, COPD , morbid obesity ( BMI > 40) , esrd W dialysis, history of > 3 months of MI, Cerebrovascular accidents
IV : constant threat to life - sepsis, ongoing ischaemia, MI <3 m
V : not expected to survive without operation
VI : declared brain dead patient who’s organs are being removed for donor purposes
oral fluids / fasting rules re surgery
fluids 2h before ( clear fluids) , 6h for solids/ non-clear liquids
mx of patients on insulin undergoing minor procedures
good glycaemic control - adjustment of usual insulin regime ( defined as HbA1C < 69)
in what circumstances should a VRII be used
more than one meal is to be missed
patients with poor glycaemic control
risk of renal injury - low eGFR/ contrast
metformin - day before surgery, day of surgery ( morning) and day of surgery ( afternoon)
before - normal
morning - od, bd : normal
afternoon - od bd normal
basically for metformin the only time u make any changes is when the medication is being taken TDS - in which case lunchtime dose is omitted
sulfonylureas - day before surgery, day of surgery ( morning) and day of surgery ( afternoon)
day before - normal
morning surgery - omit morning dose , take evening dose if BD
afternoon surgery - omit everything regardless of od, bd
sglt-2 surgery rules
omit on day only
insulin surgery rules
once daily regimens - reduce dose by 20% ( before, day of)
twice daily regimens - half morning dose on day of surgery
what are the three phases of an operation
before induction of an anaesthesia - sign in
before incision of the skin - time out
before patient leaves the operating room- sign out
what is the checklist confirmed before proceeding with an operation
Patient has confirmed: Site, identity, procedure, consent
Site is marked
Anaesthesia safety check completed
Pulse oximeter is on patient and functioning
Does the patient have a known allergy?
Is there a difficult airway/aspiration risk?
Is there a risk of > 500ml blood loss (7ml/kg in children)?
Abdominal pain, bloating and vomiting following bowel surgery
postoperative ileus
what is the bowel prep required before a colonoscopy
laxatives the day before the examination
patients required not to eat 24h before colonoscopy
what medication should be prescribed prior to surgery for patients taking prednisolone
hydrocortisone supplementation
how should total parenteral nutrition be administered
central vein like subclavian line
which anaesthetic has inherent anti emetic properties
propofol
how do you manage severe anaemia prior to surgery
pre-operative blood transfusion
how is local anaesthetic toxicity managed
IV lipid emulsion
how long post total hip replacement should low molecular weight heparin be commenced
6-12 hours after surgery
what is the action of lidocaine
blocking of sodium channels
what is a cause of AF following gi surgery
anastomotic leak - presenting about 5 days post op
mx of anastomotic leak
back to theate
when should the following feeding options be used
ng feeding
naso jejunal
pec
parenteral
ng feeding - impaired swallow, c/ i in head injury
naso-jejunal feeding - avoids aspiration, safe post oesophagogastric surgery
feeding jejunostomy - long term feeding, post upper GI surgery
percutaneous endoscopic gastrotomy - in patients who cannot undergo endoscopy
total parenteral nutritional - enteral feeding c/i
what are the adverse effects of depolarising anaesthetics
malignant hyperthermia
hyperkalaemia