Genitourinary 2 Flashcards

1
Q

Micturition

A

voiding or bladder emptying

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2
Q

Micturition requires the interplay of

A

nerves, detrusor muscle of the bladder, internal urethral sphincter (involuntary) and external urethral sphincter (voluntary, PV)

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3
Q

Neural control of lower urinary tract

A

During storage, the sympathetic system keeps the bladder relaxed, and the external sphincter is contracted.

During micturition, the parasympathetic system contracts the bladder, while the external sphincter is voluntarily relaxed.

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4
Q

Urinary or Fecal incontinence and pelvic organ prolapse are characteristics of overactive or underactive PFM?

A

underactive - your muscles cant keep them inside!

absent or weak contractions

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5
Q

Obstructive voiding or defecation, dyspareunia (painful intercourse), pelvic pain are associated with over or under active PFM?

A

overactive

cant voluntarily relax PFM

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6
Q

Only __-__% of incontinent adults eek medical care

A

20-50

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7
Q

Urinary incontinence contributes to what conditions?

A

falls
pressure sores
skin breakdown
UTIs
institutionalization
depression
isolation

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8
Q

Many people have more than one type of incontinence, most often which two together?

A

SUI
UUI

known as mixed UI

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9
Q

Stress Urinary Incontinence (SUI)

A

involuntary loss of urine on effort or physical exertion or on sneezing or coughing

occurs during activities that increase intrabdominal pressure

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10
Q

What causes stress incontinence?

A

weakness or loss of time in PFM

internal urethral sphincter failure

hypermobility of ureterovesical junction

damage to the pudendal nerve

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11
Q

Urgency Urinary incontinence (UUI) - what is it and what is is usually due to?

A

sudden compelling desire to urinate that is difficult to defer

often related to the detrusor (bladder) muscle contracting at small volumes

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12
Q

Which urinary incontinence occurs in response to triggers like running water or arriving home?

A

UUI

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13
Q

Other types of incontence

A

overactive bladder
functional (cant get up to go)
overflow
transient (temporary loss of control)

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14
Q

Some risk factors for urinary incontinence

A

high impact exercise
hormonal changes (estrogen deficiency)
SES
COPD

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15
Q

What is prostatitis?

A

inflammation of the prostate gland

can be bacterial or nonbacterial
asymptomatic or symptomatic

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16
Q

How many categories of prostatitis are there and which is most common in the clinic?

A

4

category 3 - chronic pelvic pain syndrome

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17
Q

T/F: all four categories of prostatitis involve inflammation

A

false

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18
Q

Category 1 Prostatitis

A

acute bacterial prostatis

Bacterial infection of the prostate gland from GU infection (bacteria or virus) or sexually transmitted diseases

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19
Q

Symptoms of acute bacterial prostatitis (local and systemic)

A

pain or obstruction with voiding

pain in suprapubic, rectal, sacral, low back or perineum

fever, chills, nausea, emesis, arthralgia, myalgia, and malaise

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20
Q

Category II of prostatitis

A

chronic bacterial prostatitis

recurrent infection

21
Q

Symptoms of chronic bacterial prostatitis

A

low-grade symptoms as for category 1

flare-ups of pelvic pain

voiding problems

sexual dysfunction - ED, ejaculatory pain, decline in emotional wellbeing

22
Q

Category III Prostatitis

A

IIIA - chronic prostatitis (CP)
IIIB - Chronic Pelvic Pain (CPPS)

most common in clinic

23
Q

IIIA chronic prostatitis (CP) VS IIIB Chronic Pelvic Pain (CPPS)

A

IIIA (CP) - pain and urinary dysfunction WITH inflammation but WITHOUT infection

IIIB - Pain and urinary dysfunction WITHOUT inflammation or infection (AKA chronic nonbacterial prostatitis)

24
Q

Symptoms with CP or CPPS

A

GU, lower abdomen/pelvic, low

back pain, worse by sitting squatting or bending

irritative and obstructive voiding

sexual dysfunction

disturbed quality of life

25
Q

Category IV of prostatitis

A

Asymptomatic Inflammatory Prostatitis

26
Q

How is Asymptomatic Inflammatory Prostatitis diagnosed/found?

A

WBCs and inflammatory markers are found in semen or prostate tissue, usually when looking for infertility causes or testing for prostate cancer

27
Q

What is Benign Prostatic Hyperplasia (BPH) and what is the criteria for it?

A

non-malignancy enlargement of the prostate gland

prostate volume > 30 mL along with urinary tract symptoms and bladder outlet obstruction

28
Q

___% of men over 50 experience symptoms of BPH

A

70%

29
Q

BPH risk factors

A

age over 40
family history
diabetes
heart disease with beta blocker use
obesity

30
Q

Exercise ____ the risk pf BPH

A

decreases

31
Q

How does BPH occur - what happens to cell growth ratio?

A

the ratio of new prostate cells to old prostate cells shifts in favor of lower cell death, causing increased growth (hyperplasia)

32
Q

In BPH, the cell growth/hyperplasia grows in what direction? What does this cause?

A

grows inward in the peri-urethral region, compressing the urethra, obstructing urine flow, backing it up in the ureters and pooling in the kidney

33
Q

Cancer of the prostate typically develops initially in the ____

A

periphery of the gland

34
Q

Common symptoms of BPH

A

painful urination
blood in urine
unexplained low back pain or pelvis, hip, upper thigh pain
sexual dysfunction

35
Q

What are the ways to asses BPH (testing)?

A

digital rectal exam (DRE)

prostate-specific antigen (PSA) blood test that is strongly related to prostate volume (normally < 4 ng/mL)

36
Q

Mandatory assesment of BPH

A

history screening
DRE
Urinary analysis to rule out infection

37
Q

“recommended” assessments for BPH

A

IPSS
AUA-SI
PSA

38
Q

What is the most ocmmon cancer in american men?

A

prostate

39
Q

what is the second most commmon cause of death of men behind lung cancer?

A

prostate cancer

40
Q

1 in _ men will develop prostate cancer

A

6

41
Q

_____carcinomas account for 98% of primary prostatic tumors

A

adenocarcinomas

42
Q

Prostate cancer usually starts in the ____ portion of the prostate and works its way ____

A

outer
inward

43
Q

What causes prostate cancer?

A

the exact cause is unknown

exercise may reduce risk

44
Q

At what age is it a risk factor for prostate cancer

A

> 50

45
Q

Pathogenesis of prostate cancer

A

adenocarcinomas infiltrate the stroma of the prostate and invade adjacent structures, spreads to lymphatics (lymphatic metastasis)

46
Q

Obstructive symptoms of prostate cancer are similar to BPH, what are they?

A

urinary urgency, frequency, hesitancy, dysuria, hematuria, difficulty initiating or continuing stream, decreased urine stream

47
Q

Bony metastasis may occur in prostate cancer, where does this occur?

A

axial skeleton

sacral and lumbar plexus

48
Q

Dull aches from prostate cancer in the rectal, sacral or lumbar spine may result in

A

difficulty walking

49
Q

Treatment of prostate cancer

A

radical prostatectomy - removal of whole prostate gland