Cardiovascular System Flashcards
Primordial prevention - who is it often aimed at?
risk factor reduction towards entire population through social and environmental conditions
aimed at children
through laws and national policy (adding sidewalks)
Primary prevention
reducing chances of first adverse CV event in patients with no clinical apparent CVD
Secondary prevention
decrease recurrent cardiovascular events and reduce death
Cardinal symptoms of cardiac disease
chest, neck, or arm pain or discomfort, angina, palpitations; dyspnea, syncope (fainting); fatigue, cough, cyanosis
____ and ____ are the most common symptoms of the vascular component of CV pathologic conditions
edema and leg pain
Biomarkers
BP, premature ventricular contraction, LDL-C, CRP (C-reactive protein)
What is the most common cause of hospitalization and death in the older population?
CV disease, especially coronary atherosclerosis
With aging, heart pumps __ blood and works ____
less
harder
disease-independent changes that reduce function:
reduced myocytes
cardiac fibrosis
reduction in calcium transport
lower capillary density
decrease in intracellular response to B-adrenergic stimulation (can’t respond to exercise well)
impaired autonomic reflex control of heart rate
What factors cause stiffer arterial walls and decreased lumen with aging?
increased collagen and calcium, progressive deterioration of tunica media, plaque
Arterial walls ____ with age and the aorta becomes ___ and _____
stiffen
dilated and elongated
loss of elasticity in elastin and collagen with aging most often affects which vessels?
larger and medium-sized
Are cardiac function changes with aging more apparent at rest or during exercise?
exercise
Max HR during exercise ___ with age
declines
What cardiac changes with *exercise occur with aging?
decline with maximal oxygen uptake, declined heart rate, reduced maximal cardiac output
T/F exercise can reverse some of the age associated changes in the heart
True
Female hearts are ___ and ____ than male hearts
smaller and constructed differently
Structural differences in the ____ ____ may explain why women are more prone to __________ than are men
mitral valve
mitral valve prolapse
Woman have a 3x greater risk of ______ from medication
potentially fatal arrhythmias from medication
Women have a greater incidence of ______ from thrombolytic agents
bleeding episodes
Metabolic syndrome diagnosis criteria
- elevated waist circumference (>40 men, >35 women)
- reduced HDL (<40 men and <50 women)
- increased BP (130/85 or greater)
- elevated fasting blood glucose (100 or greater)
- elevated serum triglyceride (150 or greater)
Elevated ____ levels place a person at greater risk of heart disease
total serum cholesterol
optimal total cholesterol level
about 150
optimal LDL and HDL levels
LDL - about 100
HDL - 40 in men and 50 in women