Genital Tract Infection - Mycoplasma Genitalium

Question 1

What is Mycoplasma Genitalium?

Answer 1

A bacterial STI that can cause non-gonococcal urethritis.

Question 2

What is Non-Gonococcal Urethritis/Non-Specific Urethritis?

Answer 2

Gonococcal bacteria are not identifiable on the initial swab (gram-negative diplococci).

Question 3

Causative Organisms of Non-Gonococcal Urethritis (2).

Answer 3

1. Chlamydia trachomatis (commonest).

2. Mycoplasma genitalium (more symptomatic than Chalmydia).

Question 4

Clinical Features of Mycoplasma Genitalium.

Answer 4

1. Asymptomatic.
2. Similar to Chlamydia.
3. URETHRITIS.

Question 5

Investigations of Mycoplasma Genitalium.

Answer 5

1. NAAT.
2. 1st Line : 1st Urine Sample in Morning (Men) and Vaginal Swabs (Self-Taken : Women).
3. Check positive samples for Macrolide Resistance.

Question 6

Test of Cure in Mycoplasma Genitalium.

Answer 6

Check after treatment in every positive patient.

Question 7

Management of Mycoplasma Genitalium.

Answer 7

1. Doxycycline 100mg BD for 7 Days + Azithromycin 1g STAT and then 500mg OD for 2 Days.
2. Moxifloxacin - Alternative/Complicated Infections.

Question 8

Complications of Mycoplasma Genitalium (8).

Answer 8

1. Urethritis.
2. Epididymitis.
3. Cervicitis.
4. Endometritis.
5. Pelvic Inflammatory Disease.
6. Reactive Arthritis.
7. Preterm Delivery in Pregnancy.
8. Tubal Infertility.