Genetics and Molecular Biology Flashcards

1
Q

Movement of a chromosome piece to another chromosome location

A

Transposition

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2
Q

Genes or small DNA fragments that can move to a new location

A

Transposable elements (jumping genes)

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3
Q

She discovered transposition in 1950s

A

Barbara McClintock

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4
Q

Discovery of DNA structure in 1953 by

A

James Watson and Francis Crick

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5
Q

Chromosomes composed two types of large molecules:

A

DNA and protein

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6
Q

DNA molecule organized into chain of nucleotides composed of three parts:

A

• Nitrogenous base
• 5-carbon sugar (deoxyribose)
• Phosphate group

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7
Q

Hydrogen bonds hold base on one side of helix to another base on other side

A

rungs of ladder

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8
Q

Segment of DNA that directs protein synthesis

A

Gene

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9
Q

Sum total of DNA in an organism’s chromosomes

A

Genome

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10
Q

New DNA molecule consists of one strand from original molecule and another built using that parental strand as a template

A

semi-conservative replication

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11
Q

Copy of gene message made from DNA template using RNA building blocks

A

Transcription

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12
Q

Contains ribose, instead of deoxyribose sugars; single stranded; thymine replaced by uracil

A

RNA

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13
Q

RNA translated to produce proteins. Occurs in cytoplasm

A

Translation

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14
Q

Translated to produce proteins

A

Messenger RNA (mRNA)

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15
Q

Machinery for translation

A

Transfer RNA (tRNA)

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16
Q

Machinery for translation

A

Ribosomal RNA (rRNA)

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17
Q

sequence at end signals transcription enzymes to fall off

A

Terminator DNA

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18
Q

fundamental to control of gene expression

A

Nonprotein-coding DNA

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19
Q

Sequence of three amino acids that recognize and pair with codon on mRNA

20
Q

Agents that alter DNA sequences

21
Q

Occurs in body cell

A

Somatic mutation

22
Q

Occurs in tissues that will produce sex cells

A

Germ-line mutation

23
Q

Study of chromosome behavior and structure from a genetic point of view

A

Cytogenetics

24
Q

Chromosomal piece breaks and reinserts in opposite orientation

25
Chromosomal piece breaks off and attaches to another chromosome
Translocation
26
Carries one or more extra chromosome(s), or is missing one or more chromosome(s)
Aneuploid
27
Has at least one complete extra set of chromosomes
Polyploid
28
Offspring of parental generation
First filial generation (F1)
29
Offspring of F1 plants
Second filial generation (F2)
30
Factors (alleles), which always occur in pairs, control the inheritance of various characteristics
Law of unit characters
31
For any given pair of alleles, one (dominant) may mask the expression of the other (recessive)
Law of dominance
32
Organism’s physical appearance
Phenotype
33
Genetic information responsible for contributing to phenotype
Genotype
34
Start with cross between two true-breeding parents differing for a trait
Monohybrid Cross
35
F1 plants intercrossed to produce F2 generation
Monohybrid Cross
36
Start with parents differing in two traits
Dihybrid cross
37
Factors (genes) controlling two or more traits segregate independently of each other
Law of independent assortment
38
Genes on same chromosome
Linked genes
39
Genes on different chromosomes
Unlinked genes
40
A cross between a hybrid and one of its parents. If we have desireable trait to preserve
Backcross
41
Cross between a plant having a dominant phenotype with a homozygous recessive plant. This will determine whether plant with dominant phenotype is homozygous or heterozygous
Testcross
42
Heterozygote is intermediate in phenotype to the two homozygotes
Incomplete dominance (absence of dominance)
43
exhibit range of phenotypes rather than discrete phenotypes as studied by Mendel
Quantitative traits
44
Proportions of dominant alleles to recessive alleles in a large, random mating population will remain same from generation to generation in the absence of forces that change those proportions
Hardy-Weinberg law
45
Random loss of alleles can occur if individuals do not mate as often
Small populations
46
Most significant cause of exception to H-W
Selection