Genetics and Molecular Biology Flashcards
Movement of a chromosome piece to another chromosome location
Transposition
Genes or small DNA fragments that can move to a new location
Transposable elements (jumping genes)
She discovered transposition in 1950s
Barbara McClintock
Discovery of DNA structure in 1953 by
James Watson and Francis Crick
Chromosomes composed two types of large molecules:
DNA and protein
DNA molecule organized into chain of nucleotides composed of three parts:
• Nitrogenous base
• 5-carbon sugar (deoxyribose)
• Phosphate group
Hydrogen bonds hold base on one side of helix to another base on other side
rungs of ladder
Segment of DNA that directs protein synthesis
Gene
Sum total of DNA in an organism’s chromosomes
Genome
New DNA molecule consists of one strand from original molecule and another built using that parental strand as a template
semi-conservative replication
Copy of gene message made from DNA template using RNA building blocks
Transcription
Contains ribose, instead of deoxyribose sugars; single stranded; thymine replaced by uracil
RNA
RNA translated to produce proteins. Occurs in cytoplasm
Translation
Translated to produce proteins
Messenger RNA (mRNA)
Machinery for translation
Transfer RNA (tRNA)
Machinery for translation
Ribosomal RNA (rRNA)
sequence at end signals transcription enzymes to fall off
Terminator DNA
fundamental to control of gene expression
Nonprotein-coding DNA