Genetics and Biotechnology Flashcards
PCR (2)
enabled the amplification of a small amount of DNA into millions of copies
revolutionized research
Domestication (2)
process of adapting wild plants and animals
animal domestication occurred 9,000 - 12,000 BCE
Targets of phenotypic selection (5)
structural soundness
breeding soundness
udder capacity and soundness
indicators of productivity and adaptability
visible factors affecting market price (colour, muscle thickness)
Animal breeding taget
maintaining/improving the genetic value of livestock
Genetic progress can be developed though _____________ and ___________ (describe each)
selection- breeding only certain individuals for desirable traits
culling- eliminated individuals from breeding (castration, not breeding heifers, killing)
Heritability estimate
proportion of the total variation among individuals due to genetics
High heritability % and example
> 40%
Growth
Medium heritability % and example
20-35%
Function
Behaviour
Low heritability % and example
<15%
Fertility
Stamina
any more than 0.7 on the variability scale is due to _____________
environmental immpact
Qualitative traits (2)
inherited
either or
Quantitative traits (3)
many genes plus environment contribution
continuous variation of phenotype
Primary category for economically important traits
Study of Genetics
identifies genes that can enhance animal growth, health, ability to utilize nutrients
Study of Genomics
complete set of genetic information in an organism
Nucleotide is made of
pentose sugar
phosphate group
nitrogenous base (ATGC)
Where is DNA found (percents)
98% Nucleus
2% Mitochondria
Central Dogma
DNA (dna replication),Transcription, mRNA (RNA replication), Translation, Protein
mRNA to DNA though reverse transcription
Bird chromosome types
Female ZW
Male ZZ
Alleles
different forms of the same DNA
Genotype vs phenotype
genotype is alleles and genetic makeup
phenotype is what can be seen
DNA mutations (list and describe) (6)
Simple substitution (one letter change)
Substitution (codon change)
Insertion (new letters (2 more basepairs))
Deletion(less of letters (2 less basepairs))
Duplication (double base pairs)
Inversion (read backwards)
Types of mendelian inheritance (3)
autosomal dominant (polled)
X linked (orange cats)
Autosomal recessive (red)
Types of non mendelian inheritance (5)
Polygenic inheritance (many genes involved)
Codominance (roan cattle)
Incomplete dominance (blend/middle)
Multiple alleles (colourpoint)
Sex influenced (scurs)
Discrete vs continuous traits
discrete traits have two phenotypes
continuous have multiple
6 areas of animal biotechnology
transgenic animals
xenotransplantation
animal nutrition
animal vaccines
animal breeding
embryo transfer
use of embryo transfer
to increase amount of offspring from one female
what is somatic cell nuclear transfer (5)
cloning
dolly
nucleus on body cell with desired genes is put into an egg cell
low success
Transgenic animals (2)
animal carrying foreign genes
foreign gene becomes heritable
how can transgenes be produced (4)
viral infection
microinjection
transfection
electroporation
CRISPR-Cas9
bacterial defence made to cut certain DNA out and change it