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Rosalynn's ABSITE > Genetic breast > Flashcards

Genetic breast Flashcards

1
Q

BRCA1

A

Chromosome 17
tumor suppressor gene
AD
Breast, ovarian, pancreas, prostate

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2
Q

BRCA2

A

Chromosome 13
tumor suppressor gene
AD
Breast (higher incidence in males), ovarian, prostate

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3
Q

p53

A

Li-Fraumini syndrome
Chromosome 17
AD
breast, sarcomas, brain, leukemia, adrenal cancer

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4
Q

PALB2

A

Breast, pancreatic

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5
Q

CDH1

A

Gastric, breast

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6
Q

PTEN

A

Cowden syndrome
AD
breast, endometrial, thyroid, noncancerous hamartomas

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7
Q

mismatch repair genes (MSH1, MLH1, MSH6, PMS2)

A

Lynch syndrome

colon, endometrium, ovarian, breast, stomach

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Rosalynn's ABSITE (33 decks)

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