General Questions Flashcards
What is the PRIMARY mode of CDV transmission?
Aerosolization of respiratory exudates
“Hardpad disease” is a clinical manifestation associated with CDV infection. What tissues are primarily affected?
Footpads and nose
Myoclonus (“chewing gum fits”) is a highly suggestive sign of which disease?
Canine Distemper Virus
What is the most consistent pathological finding in uncomplicated CDV infection?
Thymic atrophy
CDV inclusion bodies are most commonly found in which location?
Cytoplasmic, in epithelial cells
Which diagnostic test is considered definitive evidence of neurologic CDV infection?
Increased anti-CDV antibody in CSF
Which type of CDV vaccine is considered safest for use in nondomestic species?
Recombinant canarypoxvirus-vectored vaccine
Which environmental factors contribute to CDV’s survival outside the host?
a) High temperature and humidity
Low temperature and low humidity
What is a key characteristic of Canine Herpesvirus (CHV)?
a) It is a very stable virus in the environment.
b) It replicates optimally at temperatures below normal body temperature.
c) It primarily infects adult dogs, causing respiratory illness.
d) It causes a characteristic thickening of the gallbladder in infected puppies.
It replicates optimally at temperatures below normal body temperature.
Which of the following is the most significant source of CHV infection for newborn puppies?
a) Inhalation of aerosolized virus
b) Contact with contaminated fomites
c) Contact with infected dam’s mucosal secretions
d) Ingestion of colostrum from infected bitches
Contact with infected dam’s mucosal secretions
What is the usual outcome of CHV infection in puppies less than 1 week old?
Acute and often fatal systemic illness
What is the primary factor that makes older puppies and adult dogs relatively resistant to severe CHV infection?
Increased body temperature inhibiting viral replication
Which of the following best describes the lesions associated with systemic CHV infection in neonatal puppies?
a) Diffuse interstitial pneumonia and hepatic necrosis
b) Multifocal hemorrhagic necrosis in multiple organs
c) Cerebellar hypoplasia and retinal dysplasia
d) Lymphoid depletion and intestinal ulceration
Multifocal hemorrhagic necrosis in multiple organs
Which of the following is a distinguishing feature of CHV infection compared to Infectious Canine Hepatitis in puppies?
a) Thickened, edematous gallbladder
b) Focal areas of necrosis and hemorrhage, especially in the kidneys
c) Rapid death and characteristic lesions
d) Elevated liver enzymes
Focal areas of necrosis and hemorrhage, especially in the kidneys
What is the MAIN route of CPIV transmission?
Aerosol and fomites
CPIV is a common component of which canine respiratory disease complex?
Kennel cough (infectious tracheobronchitis)
A 5-month-old unvaccinated Labrador Retriever presents with lethargy, fever, and a dry, hacking cough. On physical examination, you note mild conjunctivitis and tonsillar enlargement. Which of the following is the MOST likely diagnosis?
a) Canine Distemper Virus (CDV)
b) Infectious Canine Hepatitis (ICH)
c) Canine Parainfluenza Virus (CPIV)
d) Canine Infectious Tracheobronchitis (CITB)
Canine Infectious Tracheobronchitis (CITB)
A 3-year-old Beagle presents with a history of lethargy, anorexia, and vomiting. On physical examination, you note icterus and corneal edema (“blue eye”). Which of the following is the MOST likely cause of the corneal edema in this case?
a) Direct viral invasion of the cornea by CDV
b) Immune complex deposition in the cornea following CAV-1 infection
c) Secondary bacterial keratitis
d) Anterior uveitis associated with CHV infection
Immune complex deposition in the cornea following CAV-1 infection
A litter of 10-day-old Golden Retriever puppies presents with sudden onset of depression, lethargy, and anorexia. One puppy has already died. On physical examination, the remaining puppies are hypothermic and have abdominal pain. Which of the following is the MOST likely diagnosis?
a) Canine Herpesvirus (CHV) infection
b) Canine Distemper Virus (CDV) infection
c) Infectious Canine Hepatitis (ICH)
d) Neonatal septicemia
Canine Herpesvirus (CHV) infection
A 4-year-old intact female German Shepherd Dog presents with a history of infertility. She has been bred multiple times but has never conceived. Which of the following infectious agents could be contributing to her infertility?
a) Canine Herpesvirus (CHV)
b) Canine Distemper Virus (CDV)
c) Infectious Canine Hepatitis (ICH)
d) Canine Parainfluenza Virus (CPIV)
Canine Herpesvirus (CHV)
A 6-month-old Cocker Spaniel presents with a 3-day history of a harsh, dry cough. The dog is otherwise bright, alert, and playful. Which of the following is the MOST likely diagnosis?
a) Canine Infectious Tracheobronchitis (CITB)
b) Canine Distemper Virus (CDV)
c) Infectious Canine Hepatitis (ICH)
d) Canine Herpesvirus (CHV) infection
Canine Infectious Tracheobronchitis (CITB)
A 12-week-old Poodle puppy presents with a 2-day history of vomiting and diarrhea. The puppy is lethargic and anorexic. You suspect ICH. Which of the following laboratory abnormalities would be MOST consistent with this diagnosis?
a) Leukocytosis and neutrophilia
b) Hypoglycemia and increased liver enzymes
c) Hypercalcemia and hyperphosphatemia
d) Anemia and thrombocytosis
Hypoglycemia and increased liver enzymes
A 9-year-old mixed breed dog presents with a history of chronic cough and exercise intolerance. Thoracic radiographs reveal an increase in linear and peribronchial markings. Which of the following is the MOST likely diagnosis?
a) Acute Canine Infectious Tracheobronchitis (CITB)
b) Canine Distemper Virus (CDV) pneumonia
c) Chronic bronchitis
d) Pulmonary neoplasia
Chronic bronchitis
A litter of 3-week-old Beagle puppies presents with sudden onset of lethargy, anorexia, and mucopurulent nasal discharge. One puppy is hypothermic and has petechial hemorrhages on its mucous membranes. Which of the following is the MOST important differential diagnosis to consider in this case?
a) Canine Herpesvirus (CHV) infection
b) Infectious Canine Hepatitis (ICH)
c) Canine Distemper Virus (CDV)
d) Neonatal septicemia
Infectious Canine Hepatitis (ICH)
